Safety and long-term efficacy of transition from sildenafil to tadalafil due to side effects in patients with pulmonary arterial hypertension.

Author: EgenlaufBenjamin, EhlkenNicola, GrünigEkkehard, HarzheimDominik, LichtblauMona, MarraAlberto, PinadoFabiola Pena

Paper Details 
Original Abstract of the Article :
Two phosphodiesterase-type 5 (PDE-5) inhibitors, sildenafil and tadalafil, are approved for treatment of pulmonary arterial hypertension (PAH). It has not yet been observed if transition from sildenafil to tadalafil is beneficial in patients suffering from adverse reactions. Aim of this study was to...See full text at original site
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引用元:
https://doi.org/10.1007/s00408-014-9657-7

データ提供:米国国立医学図書館(NLM)

Shifting Gears: From Sildenafil to Tadalafil in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a serious condition characterized by high blood pressure in the arteries of the lungs. For patients battling PAH, finding the right medication is a crucial step in their treatment journey. This research investigates the feasibility of transitioning from sildenafil to tadalafil, two common drugs used to treat PAH, for patients who experience side effects from sildenafil. The study aims to assess the long-term safety and efficacy of this switch, offering valuable insights for clinicians and patients navigating the complexities of PAH management. This study delves into the world of PAH, examining the long-term safety and efficacy of a treatment switch for patients experiencing sildenafil side effects. The study's findings have significant implications for PAH management, providing critical information for clinicians and patients.

Safety and Efficacy in the Long Haul

The researchers found that transitioning from sildenafil to tadalafil can be a safe and effective option for patients experiencing intolerable side effects. This discovery is particularly significant for patients who struggle to manage PAH while dealing with the challenges of sildenafil's side effects. The study provides valuable data for clinicians, enabling them to make informed decisions about medication changes for their PAH patients.

Navigating PAH Treatment

For patients with PAH, finding the right medication is a journey that requires careful consideration. It's essential to work closely with a healthcare professional to understand the potential benefits and risks of different treatment options. This research demonstrates the importance of individualized care for PAH patients, taking into account their unique circumstances and experiences with medication side effects. It also emphasizes the ongoing need for research to improve PAH treatment strategies and improve the quality of life for patients.

Dr.Camel's Conclusion

This research sheds light on the potential benefits of transitioning from sildenafil to tadalafil in PAH patients. It's important to remember that each patient's experience with PAH and its treatment is unique. As a wise desert traveler, I always encourage patients to consult with their healthcare provider to make informed decisions about their treatment plan.
Date :
  1. Date Completed 2015-10-28
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

25318865

DOI: Digital Object Identifier

10.1007/s00408-014-9657-7

Related Literature

SNS
PICO Info
in preparation
Languages

English

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