Paper Details 
Original Abstract of the Article :
A study of the outcome of conventional antibiotic treatment in 543 patients with acne was performed. All were treated initially with erythromycin 1 g/day and topical 5% benzoyl peroxide. The median improvement at 6 months was 78%, with an interquartile range of 67-90%. Four-hundred and eight of the ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/j.1365-2133.1989.tb08194.x

データ提供:米国国立医学図書館(NLM)

A Study of Acne Therapy with Long-Term Antibiotics

This research delves into the complex world of dermatology, specifically focusing on the effectiveness of long-term antibiotic treatment for acne. The study, involving 543 patients, aimed to determine the efficacy of a conventional approach using erythromycin and benzoyl peroxide. The researchers found that while initial treatment led to significant improvement in 78% of patients after six months, the benefit of continuing antibiotics beyond this point was negligible. This is a valuable insight for dermatologists, as it encourages a more strategic approach to acne treatment, avoiding unnecessary prolonged antibiotic use. Interestingly, the researchers observed a greater improvement in patients who switched to minocycline for the second six months compared to those who continued erythromycin. It seems that even within the realm of antibiotics, switching gears can sometimes be beneficial for patients. However, the study also highlighted the fact that males with truncal acne (acne on the chest and back) showed the poorest response to treatment, indicating a need for more tailored therapies for specific patient groups.

Implications of the Study

The study provides valuable information for healthcare professionals and individuals seeking to manage acne. It underscores the importance of individualized treatment plans and the need for careful monitoring of treatment efficacy. The findings suggest that while antibiotics can play a significant role in initial acne management, long-term use may not always be necessary and may even lead to potential side effects. This suggests that patients should discuss with their dermatologists whether long-term antibiotic treatment is truly necessary for their specific case.

Acne Management and Lifestyle

Navigating the world of acne can be quite a journey, but this study sheds light on the importance of personalized approach. It highlights that a combination of therapies may be the best way to address acne, considering both long-term and short-term goals. It is important to remember that acne is a complex condition with various contributing factors. Maintaining a healthy lifestyle, including a balanced diet, regular exercise, and adequate sleep, can contribute to overall skin health and may aid in minimizing acne breakouts. While this study provides valuable insights, it is crucial to consult with a dermatologist for an individualised treatment plan and address any concerns regarding acne management.

Dr.Camel's Conclusion

As a fellow desert dweller, I know all about the harsh conditions that can affect our skin. This research is a beacon of hope in the world of dermatology, shining a light on the importance of personalized treatment plans. It reminds us that even the most common skin condition requires a careful approach and emphasizes the importance of consulting with a qualified professional. Just like a camel navigates the vast desert, understanding the different facets of acne treatment allows us to find the right path to clear skin. Remember, a good treatment plan can be the oasis in the desert of acne!

Date :
  1. Date Completed 1990-01-26
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

2532038

DOI: Digital Object Identifier

10.1111/j.1365-2133.1989.tb08194.x

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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