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The impact of antiretroviral therapy on mortality in HIV positive people during tuberculosis treatment: a systematic review and meta-analysis.

Author: AmadasiSilvia, CohenTheodore, GrantAlison D, HoubenRein M G J, OdoneAnna, WhiteRichard G

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Antiretroviral therapy (ART) reduced the risk of death during tuberculosis treatment by around three-fifths in HIV-positive individuals.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To quantify the impact of antiretroviral therapy (ART) on mortality in HIV-positive people during tuberculosis (TB) treatment. DESIGN: We conducted a systematic literature review and meta-analysis. Studies published from 1996 through February 15, 2013, were identified by searching electr...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229142/

データ提供：米国国立医学図書館（NLM）

The impact of antiretroviral therapy on mortality in HIV positive people during tuberculosis treatment: a systematic review and meta-analysis

The co-infection of HIV and tuberculosis (TB) presents a formidable challenge for global health. This study delves into the impact of antiretroviral therapy (ART) on mortality among HIV-positive individuals during TB treatment. The authors conducted a systematic review and meta-analysis to evaluate the effectiveness of ART in reducing mortality in this vulnerable population.

Combating the Dual Epidemic

The meta-analysis clearly demonstrates the significant impact of ART in reducing mortality among HIV-positive individuals during TB treatment. The findings highlight the crucial role of ART in managing co-infection and improving outcomes for patients. This study underscores the importance of expanding access to ART globally to combat the dual epidemic of HIV and TB.

Strengthening the Fight Against HIV and TB

This study provides strong evidence for the effectiveness of ART in reducing mortality among HIV-positive individuals with TB. The findings reinforce the importance of integrating ART into TB treatment programs to improve patient outcomes and reduce the burden of these devastating diseases.

Dr.Camel's Conclusion

This comprehensive review, like a desert guide leading a caravan through treacherous terrain, sheds light on the crucial role of ART in combating the dual epidemic of HIV and TB. The findings emphasize the urgent need to expand access to ART globally, offering hope and a chance for survival for those battling these complex and deadly diseases.

Date :
  1. Date Completed 2015-07-20
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

25391135

DOI: Digital Object Identifier

PMC4229142

SNS
PICO Info
in preparation
Languages

English

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