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HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial.

Author: CoatsTimothy, EdwardsPhil, GilmoreIan, JairathVipul, KerKatharine, MannoDaniela, RobertsIan, ShakurHaleema, StanworthSimon, VeitchAndrew

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Pragmatic Clinical TrialA trial conducted in a real-world clinical setting. It evaluates the effectiveness of interventions in everyday healthcare environments.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Gastrointestinal bleeding is a serious medical emergency that causes many deaths. While tranexamic acid has been shown to reduce the need for blood transfusions in surgical patients and deaths in trauma patients, there is limited research on its effects for upper gastrointestinal bleeding. While some studies suggest it can reduce the risk of death, the quality of this research is poor and more research is needed to determine its effectiveness and safety.
Paper Details　
Original Abstract of the Article :
Gastrointestinal bleeding is a common emergency that causes substantial mortality worldwide. Acute upper and lower gastrointestinal bleeding accounts for about 75,000 hospital admissions each year in the UK and causes the death of about 10% of these patients. Tranexamic acid has been shown to reduce...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253634/

データ提供：米国国立医学図書館（NLM）

Tranexamic Acid for Gastrointestinal Bleeding: A Randomized Controlled Trial

Gastrointestinal bleeding is a common and potentially life-threatening emergency. This study explores the potential of tranexamic acid as a treatment to reduce mortality and the need for blood transfusion in patients with gastrointestinal bleeding. The researchers are conducting a randomized controlled trial to evaluate the effectiveness of tranexamic acid in this setting.

Tranexamic Acid: A Promising Treatment for Gastrointestinal Bleeding

The study aims to determine if tranexamic acid can reduce the risk of death and the need for blood transfusion in patients with gastrointestinal bleeding. Previous research has shown that tranexamic acid can be beneficial in other bleeding conditions, such as trauma, and this study seeks to assess its efficacy in the context of gastrointestinal bleeding.

A Potential Breakthrough in Gastrointestinal Bleeding Management

This research holds the potential to significantly improve the management of gastrointestinal bleeding. If tranexamic acid is found to be effective, it could offer a valuable new tool to reduce mortality and improve patient outcomes.

Dr. Camel's Conclusion

This study is like a camel trekking through the desert, seeking a solution to the challenges of gastrointestinal bleeding. The researchers' efforts to evaluate the potential of tranexamic acid could lead to a breakthrough in the treatment of this serious condition. This research underscores the importance of continuous research and the development of new therapies to address the diverse health challenges faced by patients.

Date :
  1. Date Completed 2015-08-03
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

25409738

DOI: Digital Object Identifier

PMC4253634

Related Literature

Article Analysis
・Effective treatment of gastrointestinal bleeding
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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