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Safety and Immunogenicity of purified chick embryo cell rabies vaccine (VaxiRab N) administered intradermally as post exposure prophylaxis.

Author: AndanaiahGangaboraiah, AshwinBelludi Y, MadhusudanaShampur N, NarayanaDoddabele Ha, RachanaAnnadani R, RavishHardanahalli S, ShamannaManjula, SudarshanMysore K, VijayashankarVeena

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical Trial, Phase IVPost-marketing surveillance. Monitors long-term safety/efficacy after approval.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study compared the safety and immunogenicity of an indigenously developed rabies vaccine (VaxiRab N) to a WHO-recommended vaccine (Rabipur) when administered intradermally. Both vaccines demonstrated similar safety and efficacy, supporting the use of VaxiRab N for post-exposure prophylaxis in countries with financial constraints.
Paper Details　
Original Abstract of the Article :
The affordability to rabies vaccine for intramuscular administration in post exposure prophylaxis is a major constraint. Therefore, in countries, where there are financial constraints, World Health Organization recommends intradermal rabies vaccination that reduces the quantity and cost of vaccinati...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896796/

データ提供：米国国立医学図書館（NLM）

Safety and Immunogenicity of purified chick embryo cell rabies vaccine (VaxiRab N) administered intradermally as post exposure prophylaxis

Rabies is a potentially fatal zoonotic disease, and prompt post-exposure prophylaxis is crucial for preventing infection. This study investigates the safety and immunogenicity of a purified chick embryo cell rabies vaccine, VaxiRab N, administered intradermally. The researchers compared this vaccine to a WHO-recommended rabies vaccine, Rabipur, in a post-exposure prophylaxis setting.

VaxiRab N: A Safe and Effective Rabies Vaccine

This study demonstrates the safety and effectiveness of VaxiRab N, a purified chick embryo cell rabies vaccine, administered intradermally as post-exposure prophylaxis. The researchers found that VaxiRab N was comparable to Rabipur in terms of immunogenicity and safety. This finding is particularly relevant for countries with limited resources, as it provides a more affordable option for rabies prevention.

Combating Rabies with Safe and Effective Vaccines

The study's findings are encouraging for those seeking safe and effective rabies vaccines. The researchers' demonstration of VaxiRab N's effectiveness and safety provides a valuable tool for preventing rabies infection, particularly in resource-limited settings. It's like finding a reliable oasis in the vast and dangerous desert of rabies infection, offering protection and hope for those at risk.

Dr.Camel's Conclusion

This study highlights the safety and immunogenicity of VaxiRab N, a purified chick embryo cell rabies vaccine, administered intradermally as post-exposure prophylaxis. The researchers' findings are encouraging, as they suggest that VaxiRab N can be a viable alternative to other rabies vaccines, particularly in resource-limited settings. This research contributes to the global effort to combat rabies, a devastating disease that continues to threaten human health.
Date :
  1. Date Completed 2015-07-10
  2. Date Revised 2023-11-11
Further Info :

Pubmed ID

25424951

DOI: Digital Object Identifier

PMC4896796

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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