Children with relapsed or refractory nephroblastoma: favorable long-term survival after high-dose chemotherapy and autologous stem cell transplantation.

Author: BeckJ F, EbingerM, FeuchtingerT, FurtwänglerR, GreilJ, HandgretingerR, IllhardtT, KlingebielT, LangP, SchlegelP G, SchwarzeC P

Paper Details 
Original Abstract of the Article :
BACKGROUND: High-dose chemotherapy (HDC) with autologous stem-cell rescue (ASCR) is a treatment option for pediatric patients with relapsed nephroblastoma. We present long term results of 9 patients treated between 1993 and 2013 at our center. PROCEDURE: Reinduction therapy was carried out accordin...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1055/s-0034-1390504

データ提供:米国国立医学図書館(NLM)

Refractory Nephroblastoma: A Camel's Journey Through Treatment

In the complex realm of [研究分野], where intricate pathways and delicate balances are key, we encounter challenges that require innovative solutions. This study, like a caravan traversing through the harsh desert, explores a promising approach to treating relapsed or refractory nephroblastoma in children. The authors, armed with their research tools, embarked on a mission to [主な目的], seeking to understand the effectiveness and safety of high-dose chemotherapy (HDC) with autologous stem-cell rescue (ASCR). Their findings, akin to the discovery of a hidden oasis in a desolate expanse, reveal [主要な発見] that HDC with ASCR offers a potential lifeline for young patients battling this aggressive form of cancer. This research, like a guiding star in the night sky, illuminates a path towards better treatments for children suffering from this challenging disease.

Hope for Refractory Nephroblastoma: A Camel's Perspective

The study provides a glimmer of hope in the fight against [社会的な意義] of refractory nephroblastoma. The researchers found that [研究結果], which suggests that HDC with ASCR could potentially be a valuable tool in the treatment arsenal for these children. The results are encouraging, offering hope for a brighter future for these young patients, much like a desert bloom that survives in the harshest of environments.

Navigating the Challenges of Treatment: A Camel's Wisdom

The study underscores the importance of navigating the complex landscape of [健康的なベネフィットもしくはリスク] of HDC with ASCR. The researchers highlight the need for careful monitoring and management of side effects while emphasizing the potential benefits of this treatment approach. It's like learning to navigate the treacherous dunes of the desert - we must proceed with caution, aware of the potential hazards, but also recognizing the potential rewards that lie ahead.

Dr. Camel's Conclusion

This study, like a well-worn path through the desert, provides valuable insights into the treatment of refractory nephroblastoma. The findings suggest that HDC with ASCR offers a promising avenue for battling this challenging disease, offering a lifeline for young patients and their families. As researchers, we must continue to explore new treatment options and refine existing methods, just as a camel adapts to the ever-changing landscapes of the desert, always seeking the most sustainable and effective paths.

Date :
  1. Date Completed 2015-09-10
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

25431868

DOI: Digital Object Identifier

10.1055/s-0034-1390504

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.