Paper Details

  1. Home
  2. Paper Details

The effects of pitavastatin on glucose metabolism in patients with type 2 diabetes with hypercholesterolemia.

Author: DaidoHisashi, HorikawaYukio, TakedaJun

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Pitavastatin did not worsen insulin resistance in Japanese patients with type 2 diabetes complicated by hypercholesterolemia. However, it elicited a significant decrease in fasting blood glucose in the obese group with BMI ≥ 25.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Although there have been several reports that statins cause insulin resistance that leads to the occurrence of type 2 diabetes in Caucasians, there has been no Japanese prospective studies investigating the effects of statins on the glucose metabolism system. MATERIALS AND METHODS: Our ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.diabres.2014.09.048

データ提供：米国国立医学図書館（NLM）

Pitavastatin: Navigating the Desert of Glucose Metabolism

This research explores the intersection of cholesterol management and glucose metabolism, focusing on the effects of pitavastatin, a statin drug used to lower cholesterol levels, on patients with type 2 diabetes and high cholesterol. It's like navigating a vast desert where the delicate balance of glucose metabolism is often disrupted in individuals with diabetes. The study examined the impact of pitavastatin on various glucose metabolism markers in a group of Japanese patients with type 2 diabetes and high cholesterol.

Pitavastatin's Impact on Glucose Metabolism: A Balancing Act

The study found that pitavastatin did not significantly worsen insulin resistance in these patients. However, it did lead to a decrease in fasting blood glucose levels in the group with a body mass index (BMI) of 25 or higher. This finding suggests that pitavastatin may have a positive impact on glucose metabolism in obese individuals with type 2 diabetes.

A Personalized Approach to Diabetes Management

This research sheds light on the potential benefits of pitavastatin in managing glucose metabolism in obese individuals with type 2 diabetes. However, it also highlights the importance of a personalized approach to diabetes management, considering factors like BMI and individual responses to medication.

Dr.Camel's Conclusion

This study is like a journey through the desert of diabetes management, where we learn that pitavastatin may have a positive impact on glucose metabolism in obese individuals with type 2 diabetes. The findings underscore the importance of a personalized approach to diabetes management, taking into account individual factors and the complex interplay between cholesterol and glucose metabolism.

Date :
  1. Date Completed 2015-07-14
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

25458331

DOI: Digital Object Identifier

10.1016/j.diabres.2014.09.048

Related Literature

Article Analysis
・Side Effects of pitavastatin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.