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Treatment satisfaction in postmenopausal women suboptimally adherent to bisphosphonates who transitioned to denosumab compared with risedronate or ibandronate.

Author: AgodoaIrene, BonnickSydney, BrownJacques P, FerreiraIrene, HoPei-Ran, PalaciosSantiago, Van den BerghJoop P

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Postmenopausal women with low adherence to oral bisphosphonates reported greater treatment satisfaction when transitioned to denosumab compared to a monthly oral bisphosphonate.
Paper Details　
Original Abstract of the Article :
CONTEXT: For many patients, adhering to postmenopausal osteoporosis treatment is a challenge. Higher treatment satisfaction is associated with greater persistence with these therapies, which is associated with better outcomes. OBJECTIVE: This study aimed to evaluate the change in treatment satisfac...See full text at original site
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引用元：
https://doi.org/10.1210/jc.2014-3594

データ提供：米国国立医学図書館（NLM）

Denosumab: A New Option for Postmenopausal Osteoporosis

Postmenopausal osteoporosis is a common condition that can lead to fractures and other health complications. This study examines the treatment satisfaction of postmenopausal women who transitioned from suboptimally adherent oral bisphosphonates to denosumab compared to those who switched to monthly oral bisphosphonates. This research is crucial for understanding the potential benefits and challenges of different osteoporosis treatment options, particularly for patients with adherence issues.

Denosumab: Improved Treatment Satisfaction

The study found that women who transitioned to denosumab reported significantly greater improvements in treatment satisfaction compared to those who switched to monthly oral bisphosphonates. These findings suggest that denosumab may be a valuable option for women with low adherence to oral bisphosphonates, potentially leading to better treatment persistence and overall health outcomes.

Tailoring Osteoporosis Treatment: A Key to Success

Managing osteoporosis requires a personalized approach, considering factors like bone health, individual preferences, and treatment adherence. This study underscores the importance of tailoring treatment to meet individual needs, highlighting the potential of denosumab as a valuable option for women who struggle with adherence to oral bisphosphonates.

Dr.Camel's Conclusion

Think of a camel caravan traversing a desert, with each camel carrying its own unique burdens. Just as a camel needs to adapt its pace and strategy based on its load and the terrain, so too do individuals with osteoporosis need a personalized approach to treatment. This study offers a valuable oasis in the desert of osteoporosis management, reminding us that denosumab could be a powerful tool for improving treatment satisfaction and potentially leading to better outcomes for women who struggle with adherence to traditional medications.
Date :
  1. Date Completed 2015-05-12
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25514106

DOI: Digital Object Identifier

10.1210/jc.2014-3594

Related Literature

Article Analysis
・Effective treatment of osteoporosis
SNS
PICO Info
in preparation
Languages

English

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