Paper Details

  1. Home
  2. Paper Details

Long-acting anticholinergic agents in patients with uncontrolled asthma: a systematic review and meta-analysis.

Author: ByunM K, JungJ Y, KimH J, KimS W, KimY H, LeeS W, MoonJ-Y, ParkJ-Y, ParkY B, YooK H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review assessed the benefits of tiotropium in patients with poorly controlled asthma. The addition of tiotropium to inhaled corticosteroids resulted in improvements in lung function, reduced risk of severe exacerbation, and improved quality of life.
Paper Details　
Original Abstract of the Article :
SETTING: A novel effective treatment is necessary for severe asthma. OBJECTIVE: To review clinical trials examining the role of tiotropium in patients with poorly controlled asthma despite inhaled corticosteroid use with or without long-acting β₂-agonists. DESIGN: A computerised search of electron...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.5588/ijtld.14.0275

データ提供：米国国立医学図書館（NLM）

Tiotropium: A Potential Game-Changer for Uncontrolled Asthma

The search for effective treatments for [Severe Asthma] is a challenging quest. This study investigates the potential of tiotropium, a long-acting anticholinergic agent, in patients with poorly controlled asthma, even after conventional inhaled corticosteroids with or without long-acting β₂-agonists. The study, a systematic review and meta-analysis, analyzed five clinical trials involving over 1600 patients. The results show that tiotropium improved lung function, reduced the risk of severe exacerbations, and enhanced asthma-related quality of life. These findings suggest that tiotropium could be a valuable addition to the treatment arsenal for severe asthma patients. However, long-term trials are needed to clarify its safety and efficacy before widespread use.

Tiotropium's Potential Benefits for Asthma Control

The study's findings are encouraging, showing that tiotropium significantly improved lung function and reduced asthma exacerbations. These findings offer a potential lifeline for patients with severe asthma who have not found relief with standard treatments.

Navigating Asthma Management: A Journey of Hope

The results of this research are promising, and while long-term trials are necessary, they offer a glimmer of hope for individuals struggling with severe asthma. The findings highlight the potential benefits of tiotropium in improving lung function and reducing asthma exacerbations. This could lead to better asthma management and improved quality of life for many patients.

Dr. Camel's Conclusion

Finding the right treatment for asthma can be like searching for a mirage in the desert – elusive and often frustrating. This research offers a potential oasis, suggesting that tiotropium might be a valuable tool in the battle against uncontrolled asthma. While further research is needed, this study gives us hope for a future where asthma can be effectively managed and patients can live fuller lives.

Date :
  1. Date Completed 2015-08-18
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25517806

DOI: Digital Object Identifier

10.5588/ijtld.14.0275

Related Literature

Article Analysis
・Effective treatment of asthma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.