Paper Details 
Original Abstract of the Article :
The activity of 18 vitamin D analogs on soft tissue calcification and growth impairment in neonatal rats and their effect on bone calcium mobilization, intestinal calcium absorption and binding to intestinal 1,25-dihydroxyvitamin D3 receptors in adult rats were compared. Depending on the chemical mo...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/BF00303129

データ提供:米国国立医学図書館(NLM)

Vitamin D Derivatives: A Potential for Therapeutic Benefits Without Hypercalcemia

The world of vitamin D analogs, like a desert teeming with diverse plant life, is filled with potential for therapeutic benefits. This study, like a botanist meticulously studying the unique properties of desert plants, explores the activity of 18 vitamin D analogs on calcium metabolism and their potential for therapeutic applications. The researchers investigated the effects of these analogs on soft tissue calcification, calcium mobilization, and intestinal calcium absorption in rats.

Potential for Vitamin D Derivatives with Targeted Effects

This study, like a desert explorer discovering a hidden spring with unique properties, highlights the potential for developing vitamin D derivatives with specific therapeutic actions. The researchers found that certain modifications to the vitamin D molecule could alter its activity, leading to potential therapeutic applications without the undesirable side effects of hypercalcemia.

Exploring the Therapeutic Potential of Vitamin D Derivatives

This research, like a desert oasis offering a refreshing respite, provides valuable insights into the therapeutic potential of vitamin D derivatives. The findings suggest that by carefully modifying the vitamin D molecule, researchers could develop drugs with targeted effects, potentially leading to new treatments for a variety of conditions. It's a reminder that even in the seemingly barren landscape of medicine, there are often opportunities for innovation and discovery.

Dr.Camel's Conclusion

The world of vitamin D analogs is a fascinating and complex one, much like a vast and varied desert landscape. This study, like a camel caravan carefully navigating the desert terrain, reveals the potential for developing vitamin D derivatives with specific therapeutic actions. It's a reminder that even in the seemingly barren landscape of medicine, there are often opportunities for innovation and discovery.

Date :
  1. Date Completed 1989-12-13
  2. Date Revised 2019-09-03
Further Info :

Pubmed ID

2554850

DOI: Digital Object Identifier

10.1007/BF00303129

Related Literature

SNS
PICO Info
in preparation
Languages

English

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