Expanding substance use treatment options for HIV prevention with buprenorphine-naloxone: HIV Prevention Trials Network 058.

Author: , AramrattanaApinun, BeauchampGeetha, BurnsDavid N, CelentanoDavid D, ChawarskiMarek, ChenRay Y, DonnellDeborah, DyeBonnie J, FuLiping, JacksonJ Brooks, LucasGregory M, MaJun, MetzgerDavid S, RichardsonPaul, RoseScott M, RuanYuhua, ShaoYiming, ShinKatherine, SugarmanJeremy, WeiLiu

Paper Details 
Original Abstract of the Article :
BACKGROUND: Injection opioid use plays a significant role in the transmission of HIV infection in many communities and several regions of the world. Access to evidence-based treatments for opioid use disorders is extremely limited. METHODS: HIV Prevention Trials Network 058 (HPTN 058) was a randomi...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/25564105

データ提供:米国国立医学図書館(NLM)

Buprenorphine-Naloxone for HIV Prevention: Expanding Treatment Options

This study investigates the potential of buprenorphine-naloxone (BUP/NX), a medication-assisted treatment (MAT) strategy, for reducing HIV incidence among people who inject drugs (PWID). The study compares the effects of two BUP/NX treatment strategies, short-term and long-term, on drug use and injection-related risk behaviors. The researchers found that both treatment strategies were associated with reductions in injection-related risk behavior, while long-term BUP/NX was more effective in reducing opioid injection. This study underscores the potential of BUP/NX as a valuable tool for HIV prevention among PWID.

Expanding Treatment Options for Opioid Use Disorder

This study highlights the potential of BUP/NX as a valuable tool for reducing HIV incidence among PWID. The findings suggest that BUP/NX, particularly in a long-term treatment setting, can effectively reduce drug use and injection-related risk behaviors, contributing to broader HIV prevention efforts.

Navigating the Desert of Addiction

Opioid addiction is a challenging and often devastating condition. This study provides a beacon of hope by demonstrating the potential of BUP/NX as a valuable tool for reducing HIV incidence among PWID. The findings suggest that BUP/NX could play a crucial role in efforts to reduce HIV transmission and improve the health and well-being of PWID.

Dr.Camel's Conclusion

This study underscores the importance of expanding treatment options for opioid use disorder. The findings suggest that BUP/NX, particularly in a long-term treatment setting, can effectively reduce drug use and injection-related risk behaviors, contributing to broader HIV prevention efforts.

Date :
  1. Date Completed 2015-05-18
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

25564105

DOI: Digital Object Identifier

NIHMS651868

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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