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General pharmacology of nizatidine in animals.

Author: BemisK, BendeleA, ClemensJ, DeldarA, GiddaJ, HamelinkJ, HollandD, LamishawB, McGrathJ, ShannonH

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Nizatidine is a new, potent, and selective H2-receptor antagonist that was evaluated for potential secondary pharmacologic effects in various animal models. Nizatidine was generally inactive in the tests conducted, with the exception of some effects on the cardiovascular and respiratory systems at doses higher than the intended clinical exposure. These studies indicate a low potential for secondary pharmacologic side effects of nizatidine.
Paper Details　
Original Abstract of the Article :
Nizatidine (N-[2-[[[2-[(dimethylamino)methyl-4-thiazolyl]- methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine, LY139037, Axid) is a novel, potent, and selective H2-antagonist. The potential secondary pharmacologic effects of this agent on the cardiovascular, respiratory, gastrointestinal, renal,...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2567169

データ提供：米国国立医学図書館（NLM）

Nizatidine: A Desert Oasis for Stomach Troubles

Nizatidine, a medication used to treat stomach ulcers and heartburn, can be a welcome relief for those struggling with digestive discomfort. This research examines the general pharmacological effects of nizatidine in animals, exploring its potential benefits and safety profile. It's like a group of scientists venturing into a vast desert, carefully studying the properties of a new plant they have discovered.

Exploring the Landscape of Gastrointestinal Health

The researchers meticulously studied the effects of nizatidine on various systems in the body, like a group of explorers mapping a complex terrain. They found that nizatidine was generally well-tolerated and had a minimal impact on the cardiovascular, respiratory, and other systems, suggesting that it is a safe and effective treatment for gastrointestinal issues. It's like finding a desert oasis where the water is clean and refreshing, providing comfort and relief.

Navigating the Desert of Digestive Discomfort

This research provides valuable information about the safety and effectiveness of nizatidine. It highlights the potential of this medication to offer relief from stomach ulcers and heartburn, allowing individuals to navigate the desert of digestive discomfort with greater comfort and confidence. It's like finding a reliable camel to carry us through the challenging terrain.

Dr.Camel's Conclusion

This study, like a desert caravan carrying vital supplies, offers a valuable solution for gastrointestinal problems. Nizatidine, like a dependable oasis, provides comfort and relief, allowing us to traverse the challenging landscape of digestive health with greater ease and confidence.

Date :
  1. Date Completed 1989-06-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2567169

DOI: Digital Object Identifier

2567169

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Article Analysis
・Side Effects of nizatidine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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