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[Beta receptor block versus calcium antagonism. A comparative study of bopindolol and nifedipine with special regard to quality of life].

Author: BräutigamM, WelzelD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This randomized, double-blind trial compared the antihypertensive efficacy and tolerability of bopindolol and nifedipine in 203 patients with hypertension. Bopindolol effectively lowered blood pressure in a dose-dependent manner, with most patients requiring 1 mg once daily for optimal control. Nifedipine also effectively lowered blood pressure, but with more side effects, including tiredness, dizziness, and leg edema. Bopindolol was well tolerated with fewer side effects.
Paper Details　
Original Abstract of the Article :
203 patients with a diastolic blood pressure higher than 100 mmHg were included in a randomized, double-blind trial to compare the antihypertensive efficacy of different daily dosages of bopindolol (Wandonorm) (0.05 mg, 0.5 mg, 1 mg, 2 mg) and nifedipine (2 x 20 mg). After 4 weeks of therapy blood p...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2568838

データ提供：米国国立医学図書館（NLM）

Bopindolol vs. Nifedipine: A Comparative Study of Antihypertensive Agents

This randomized, double-blind trial, published in the Journal of Cardiovascular Pharmacology, compared the antihypertensive efficacy of bopindolol and nifedipine in patients with high blood pressure. The study evaluated the effectiveness of different dosages of both drugs, assessing blood pressure normalization and overall tolerance. This is like comparing two different paths through the desert – one path might be more direct, while another might offer a smoother journey.

Bopindolol: A Well-Tolerated Antihypertensive Agent

The study found that both bopindolol and nifedipine were effective in lowering blood pressure. However, bopindolol was generally better tolerated than nifedipine, with fewer side effects, such as tiredness, dizziness, and leg edema.

Managing High Blood Pressure: Choosing the Right Approach

This study emphasizes the importance of individualized treatment approaches for high blood pressure. Choosing the right medication, dosage, and monitoring strategy can significantly impact patient outcomes. This is like selecting the right camel for a desert trek – the ideal choice can make all the difference.

Dr. Camel's Conclusion

This study provides valuable insights into the comparative efficacy and tolerability of bopindolol and nifedipine for treating high blood pressure. The findings highlight the importance of personalized treatment decisions to ensure optimal outcomes and minimize side effects.

Date :
  1. Date Completed 1989-08-18
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2568838

DOI: Digital Object Identifier

2568838

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in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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