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Immunogenicity and safety of purified chick-embryo cell rabies vaccine under Zagreb 2-1-1 or 5-dose Essen regimen in Chinese children 6 to 17 years old and adults over 50 years: a randomized open-label study.
Author: LiRongCheng, LiYanPing, MoZhaojun, NongYi, PellegriniMichele, WenHuiChun, WenShuQing, XieFang
Original Abstract of the Article :
The aim of this Phase IIIb, open-label, randomized study was to demonstrate the non-inferiority of immune responses and to assess the safety of a purified chick-embryo cell rabies vaccine (PCECV) in healthy Chinese children (6 to 17 years) and older adults (≥51 years) following 2 alternative intramu...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514244/
データ提供:米国国立医学図書館(NLM)
Evaluating the Immunogenicity and Safety of Rabies Vaccine Regimens
This study investigates the immunogenicity and safety of a purified chick-embryo cell rabies vaccine (PCECV) in Chinese children and adults, comparing the effectiveness of two different post-exposure prophylaxis (PEP) regimens: the 4-dose Zagreb regimen and the 5-dose Essen regimen. Imagine a desert landscape where travelers, like those exposed to rabies, need protection from a potentially deadly threat. This research explores the effectiveness of different vaccination strategies to ensure robust immunity and safe travel through this dangerous terrain.
Finding the Right Path to Rabies Protection
The study found that both Zagreb and Essen regimens were highly effective in inducing strong immune responses against rabies, providing robust protection for both children and adults. This is like discovering a reliable and safe path through the desert, offering travelers the assurance of a safe journey. The study's findings support the use of either regimen, providing valuable guidance for healthcare providers in managing rabies exposure.
Safeguarding Against Rabies: A Global Challenge
This research is a testament to the ongoing efforts to develop safe and effective vaccines against rabies, a global health threat. It's like establishing a network of oases across the desert, providing vital protection for travelers and communities. The study's findings underscore the importance of continued research to develop even better vaccines and strategies for preventing rabies, a disease that continues to claim lives around the world.
Dr.Camel's Conclusion
This research offers valuable insights into the effectiveness and safety of different rabies vaccination regimens, providing healthcare providers with robust evidence to guide their practices. It's like discovering a hidden map leading to a network of oases across the desert, offering travelers a safe and reliable route to protection. The study's findings underscore the importance of continued research to ensure effective and accessible rabies vaccination for all, promoting a safer and healthier world.
Date :
- Date Completed 2015-12-15
- Date Revised 2023-11-11
Further Info :
Related Literature
English
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