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[Adverse effects of calcium channels blockers used as tocolytic treatment].

Author: ClouqueurE, CoulonC, DebargeV, DeruelleP, GautierS, SubtilD, VaastP

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study reviewed the side effects of calcium channel blockers used for tocolysis in France. Adverse effects occurred in 2-6% of patients using nifedipine, with 0.9-1.9% being severe. Nicardipine showed less evidence, but severe cardiovascular complications were reported more frequently. Meta-analyses showed fewer maternal side effects with calcium channel blockers compared to beta-agonists.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Tocolysis with calcium channel blockers is widespread in France. However, these molecules are off label use for this indication. The objective of this work is to give an update on all the side effects of calcium channel blockers published or reported to the National Bank of Pharmacovigila...See full text at original site
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引用元：
https://doi.org/10.1016/j.jgyn.2014.12.012

データ提供：米国国立医学図書館（NLM）

Adverse Effects of Calcium Channel Blockers in Tocolysis

The study examines the potential side effects of calcium channel blockers used for tocolysis, a treatment that aims to delay premature labor. Imagine a camel carrying a precious cargo (the baby), but the journey (pregnancy) is ending sooner than expected. This study delves into the potential risks of using calcium channel blockers to 'slow down' the journey. The authors reviewed published data and reported cases, finding that while calcium channel blockers generally have fewer side effects than beta-agonists, there are still potential risks, particularly with Nicardipine.

Weighing the Risks and Benefits

The study highlights the importance of careful consideration when choosing a tocolysis treatment. While calcium channel blockers may be a valuable tool for delaying premature labor, it's crucial to be aware of the potential side effects and to carefully monitor patients. It's like navigating a sandstorm in the desert - you need to be vigilant and make informed decisions to ensure a safe journey. The study also emphasizes the need for more research to better understand the long-term effects of these drugs.

Making Informed Decisions About Tocolysis

This research emphasizes the need for open communication between patients and healthcare professionals when discussing tocolysis. By understanding the potential risks and benefits of each treatment option, patients can make informed decisions that are right for them. Remember, like a camel choosing its path through the desert, we must consider all factors and choose a route that leads to a safe and healthy outcome.

Dr. Camel's Conclusion

This study serves as a reminder that even seemingly safe treatments can have unexpected side effects. It's essential to approach healthcare decisions with caution and to seek the advice of experienced professionals. Like a camel navigating a treacherous desert, we must be wise and discerning in our choices to ensure a smooth and safe journey.

Date :
  1. Date Completed 2015-12-22
  2. Date Revised 2015-03-21
Further Info :

Pubmed ID

25726253

DOI: Digital Object Identifier

10.1016/j.jgyn.2014.12.012

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・Side Effects of nicardipine
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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