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Triple combination treatment with fractional CO2 laser plus topical betamethasone solution and narrowband ultraviolet B for refractory vitiligo: a prospective, randomized half-body, comparative study.

Author: ChenHong-Duo, GaoXing-Hua, LiLi, LiLu, QiuLi, SunYan, WuYan

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Vitiligo, a skin condition that causes white patches, is often difficult to treat on the hands, feet, and bony areas. This study examined a combination of laser treatment, a strong steroid cream, and UV light therapy in 25 people with vitiligo in these areas. More than 40% of people saw a significant improvement in pigmentation, and patient satisfaction was higher than in the control group. Side effects were mild. This combination treatment could be a potential option for treating difficult cases of vitiligo.
Paper Details　
Original Abstract of the Article :
Vitiligo on extremities and/or bony prominences is very resistant to treatment. Twenty-five patients with symmetrical and stable vitiligo on extremities and/or bony prominences were enrolled. The treatment side received fractional carbon dioxide laser followed by topical compound betamethasone solut...See full text at original site
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引用元：
https://doi.org/10.1111/dth.12202

データ提供：米国国立医学図書館（NLM）

Combating Refractory Vitiligo: A Triple Threat Approach

This study investigates the efficacy of a triple combination treatment for refractory vitiligo, a condition characterized by depigmentation of the skin. The authors conducted a prospective, randomized half-body, comparative study, comparing the effects of a triple combination therapy involving fractional carbon dioxide laser, topical betamethasone solution, and narrowband ultraviolet B phototherapy to a control group receiving laser treatment plus phototherapy. Their findings suggest that the triple combination therapy may be a more effective treatment option for refractory vitiligo, achieving greater repigmentation and improved patient satisfaction compared to the control group.

Reversing Depigmentation: A Journey Through the Desert of Skin

This research, like a skilled artisan carefully restoring a weathered piece of desert stone, delves into the complex world of vitiligo treatment. It's a reminder that finding effective therapies for this condition requires a multi-pronged approach, like a caravan strategically navigating a challenging desert landscape. This study highlights the potential of combining different therapies to achieve better outcomes and improve the quality of life for those affected by vitiligo.

Seeking Professional Guidance for Skin Concerns

This study emphasizes the importance of consulting with a healthcare professional for any skin concerns, like a desert traveler seeking guidance from a knowledgeable guide. It's crucial to discuss your treatment options and potential side effects before making any decisions. Early intervention and personalized treatment plans can significantly impact the outcome of vitiligo and improve overall skin health.

Dr. Camel's Conclusion

This study, like a desert oasis offering a refreshing respite from the harsh elements, highlights the potential of a triple combination therapy for effectively treating refractory vitiligo. It's a reminder that seeking professional guidance and exploring innovative treatment options can offer hope and improve the quality of life for those affected by this challenging condition.
Date :
  1. Date Completed 2016-03-10
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

25753514

DOI: Digital Object Identifier

10.1111/dth.12202

Related Literature

Article Analysis
・Effective treatment of vitiligo
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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