Effects of D-timolol on intraocular pressure (IOP), beta blocking activity, and the dynamic changes of drug concentrations in aqueous humor.

Author: JiX C, ZhaoF, ZhengY Z

Paper Details 
Original Abstract of the Article :
L-timolol has been used successfully in the treatment of glaucoma. Because of its powerful beta blocking activity, however, more and more side effects have been reported. D-timolol, an optic isomer of L-timolol with much less beta blocking activity, was noted to have similar ocular hypotensive effec...See full text at original site
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引用元:
https://doi.org/10.1089/jop.1989.5.271

データ提供:米国国立医学図書館(NLM)

D-Timolol: A Promising Antiglaucoma Agent with Reduced Side Effects

Glaucoma, a serious eye condition, affects millions around the world. This study examines the potential of D-timolol, an optical isomer of L-timolol, as a new treatment for glaucoma. The authors compare the ocular hypotensive effects of D-timolol with those of L-timolol, highlighting D-timolol's potential to provide similar therapeutic benefits with fewer side effects. Their research offers valuable insights into the potential of D-timolol as a promising alternative for glaucoma management.

D-Timolol Demonstrates Comparable Ocular Hypotensive Effects with Fewer Side Effects

This study provides compelling evidence for the potential of D-timolol as a promising alternative for glaucoma treatment. D-timolol effectively reduced intraocular pressure, demonstrating comparable ocular hypotensive effects to L-timolol, while exhibiting significantly less beta-blocking activity. These findings suggest that D-timolol may offer a more favorable therapeutic profile, potentially minimizing the occurrence of side effects associated with L-timolol.

Exploring New Avenues for Glaucoma Treatment

This study underscores the ongoing search for safer and more effective treatments for glaucoma. D-timolol's promising profile suggests a potential shift in glaucoma management, potentially offering a more favorable therapeutic option for patients. As we continue to delve into the complexities of glaucoma, the pursuit of new and innovative treatments remains a crucial endeavor.

Dr.Camel's Conclusion

Like a desert oasis offering respite from the scorching sun, D-timolol emerges as a potential beacon of hope for individuals facing glaucoma. This study showcases the potential of D-timolol to provide effective treatment while minimizing side effects. By exploring new avenues for glaucoma management, we can continue to improve the lives of those affected by this vision-threatening condition.

Date :
  1. Date Completed 1990-04-26
  2. Date Revised 2019-10-29
Further Info :

Pubmed ID

2576432

DOI: Digital Object Identifier

10.1089/jop.1989.5.271

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English

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