Topical nitrogen mustard in early mycosis fungoides. A 12-year experience.

Author: SøgaardH, Thestrup-PedersenK, ZachariaeH

Paper Details 
Original Abstract of the Article :
A 12-year experience in thirty-three patients suffering from early mycosis fungoides in plaque stage confirms the effectiveness of topical nitrogen mustard therapy. Fourteen patients were in complete remission at the latest time of observation and 7 in partial remission. The probability of freedom f...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2578706

データ提供:米国国立医学図書館(NLM)

Topical Nitrogen Mustard: A Treatment Option for Early Mycosis Fungoides

The field of dermatology is always seeking better treatments for skin conditions, particularly those that can be difficult to manage. This study explores the effectiveness of topical nitrogen mustard therapy for early mycosis fungoides, a type of cutaneous T-cell lymphoma. Researchers examined a 12-year experience with this therapy in 33 patients, analyzing its efficacy, remission rates, and safety profile.

Topical Nitrogen Mustard: Effective Treatment for Early Mycosis Fungoides

The study reveals that topical nitrogen mustard therapy is an effective treatment option for early mycosis fungoides. A significant number of patients experienced complete or partial remission, highlighting the potential of this treatment to control the disease progression. The long-term follow-up data demonstrates that the therapeutic benefits can extend for several years, offering hope for long-term disease management.

Understanding the Risks and Benefits of Topical Nitrogen Mustard

While the study highlights the effectiveness of topical nitrogen mustard, it also acknowledges the potential for side effects. Although the overall tolerability was good, some patients experienced contact dermatitis, necessitating the discontinuation of treatment. This emphasizes the importance of careful patient selection and close monitoring for potential adverse reactions.

Dr.Camel's Conclusion

This research on topical nitrogen mustard therapy for early mycosis fungoides offers a valuable insight into the potential of this treatment approach. It's like finding a hidden oasis in the desert of dermatological treatment options, providing a possible solution for managing this challenging skin condition. However, as with any treatment, it is crucial to consider the potential risks and benefits and to ensure that the treatment is administered under appropriate medical supervision.

Date :
  1. Date Completed 1985-03-21
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

2578706

DOI: Digital Object Identifier

2578706

Related Literature

SNS
PICO Info
in preparation
Languages

English

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