Protective effects of valsartan and benazepril combined with atorvastatin on cardiorenal syndrome in rats.

Author: ChenJ, HuY-J, PengD-F, TangS-Y

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To study the protective effects of valsartan (Val) and benazepril, (Ben) combined with atorvastatin (Ato), on cardiorenal syndrome (CRS) in rats. MATERIALS AND METHODS: After establishing cardiorenal syndrome model, the rats were randomly divided into control, Ato, Ben+Ato and Val+Ato gr...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/25807427

データ提供:米国国立医学図書館(NLM)

Valsartan and Benazepril for Cardiorenal Syndrome

The world of cardiorenal syndrome (CRS) can be a daunting desert, with interconnected heart and kidney problems creating a complex and challenging landscape. This study explored the potential protective effects of valsartan (Val) and benazepril (Ben), combined with atorvastatin (Ato), on CRS in a rat model. The researchers examined the impact of these medications on various biomarkers of heart and kidney function, including serum creatinine, blood urea nitrogen, and blood pressure.

Protecting the Oasis: Valsartan and Benazepril for CRS

This study suggests that valsartan and benazepril, in combination with atorvastatin, may provide protection against the progression of CRS in rats. The study found that these medications significantly reduced biomarkers of kidney damage and improved heart function. This research provides valuable insights into the potential of these medications for managing CRS in humans.

Navigating the Desert of CRS: A Multifaceted Approach

This research highlights the importance of a multifaceted approach to managing CRS, combining medications that address both heart and kidney function. It underscores the need for further research to understand the complex interplay of heart and kidney health and develop more effective treatment strategies.

Dr.Camel's Conclusion

This study offers a glimmer of hope in the desert of cardiorenal syndrome, suggesting that valsartan and benazepril, combined with atorvastatin, may offer significant protection against the progression of this complex condition. It encourages further research to explore the full potential of these medications for managing CRS and improve the quality of life for patients facing this challenge.

Date :
  1. Date Completed 2015-09-23
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25807427

DOI: Digital Object Identifier

25807427

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Languages

English

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