Effect of long-term acid gastric inhibition on bacterial translocation in cirrhotic rats.

Author: GonzalezBegoña, GuarnerCarlos, Guarner-ArgenteCarlos, JuárezCándido, MirelisBeatriz, MonésJoan, NietoJuan C, SorianoGermán, SánchezElisabet, VidalSilvia

Paper Details 
Original Abstract of the Article :
Bacterial translocation (BT) related to intestinal bacterial overgrowth (IBO) plays an important role in the pathogenesis of bacterial infections in cirrhosis. Inhibition of acid gastric secretion promotes IBO and might favor BT. We evaluated the effect of long-term inhibition of acid gastric secret...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/25822866

データ提供:米国国立医学図書館(NLM)

Acid Gastric Inhibition and Bacterial Translocation: A Desert of Microbial Interactions

In the intricate desert of the human gut, a delicate balance exists between the various microbial inhabitants. This study explores the impact of acid gastric inhibition, a process that reduces stomach acid production, on bacterial translocation, a phenomenon where bacteria from the gut migrate to other parts of the body. Researchers, like explorers venturing into the unseen world of the gut microbiome, investigated the effects of long-term acid gastric inhibition in cirrhotic rats. Their findings suggest that inhibiting acid gastric secretion can promote bacterial overgrowth in the gut, potentially increasing the risk of bacterial translocation and subsequent infections.

The Microbiome's Desert: A Complex Landscape of Interactions

This study highlights the complex interplay between gastric acid production and bacterial translocation in the gut. The researchers found that inhibiting acid gastric secretion can lead to bacterial overgrowth, increasing the risk of bacteria moving to other parts of the body. This underscores the delicate balance of the gut microbiome and the potential consequences of disrupting this balance through interventions like acid gastric inhibition.

Navigating the Desert of Gut Health: Seeking Professional Guidance

The desert of gut health can be a delicate and complex landscape. This study reminds us that interventions aimed at altering the gut microbiome, such as acid gastric inhibition, can have unintended consequences. If you are considering any interventions that affect your gut health, it's essential to consult with your healthcare provider to weigh the potential benefits and risks. Remember, navigating this desert requires a careful and informed approach.

Dr.Camel's Conclusion

This study reminds us that the desert of the gut microbiome is a delicate ecosystem with complex interactions. Inhibiting acid gastric secretion can disrupt this balance, potentially leading to bacterial overgrowth and increased risk of bacterial translocation. It's essential to consult with your healthcare provider to determine the best approach for managing gut health and to navigate this desert with caution.

Date :
  1. Date Completed 2016-02-01
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25822866

DOI: Digital Object Identifier

00042737-201505000-00014

Related Literature

SNS
PICO Info
in preparation
Languages

English

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