Examining the Time to Therapeutic Effect of Pregabalin in Spinal Cord Injury Patients With Neuropathic Pain.

Author: CardenasDiana D, EmirBirol, ParsonsBruce

Paper Details 
Original Abstract of the Article :
In 2 large-scale, placebo-controlled trials, pregabalin improved both pain and pain-related sleep interference in patients with neuropathic pain due to spinal cord injury (SCI). In both trials, pregabalin found statistically significant improvement compared with placebo after 1 week of treatment. Ho...See full text at original site
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引用元:
https://doi.org/10.1016/j.clinthera.2015.02.028

データ提供:米国国立医学図書館(NLM)

Pregabalin: A Potential Treatment for Neuropathic Pain in SCI

We're navigating the challenging terrain of neuropathic pain, a type of chronic pain caused by damage to the nervous system. Imagine a desert traveler, where a thorn in their foot can lead to persistent and agonizing pain. This research focuses on the use of pregabalin, a medication that is often used to treat neuropathic pain, specifically in patients with spinal cord injury (SCI).

Easing the Burden of Neuropathic Pain

The authors analyzed data from two large-scale, placebo-controlled trials, demonstrating that pregabalin effectively reduced pain and improved sleep in patients with neuropathic pain related to SCI. It's like discovering a hidden oasis in the desert, providing relief from the burning heat and parched thirst. The authors found that pregabalin's therapeutic effects were evident as early as one week after treatment initiation.

Understanding the Timing of Relief

This research emphasizes the importance of understanding the timing of pregabalin's therapeutic effects, highlighting its potential to provide rapid relief from neuropathic pain. It's like knowing when to expect the arrival of a life-saving caravan in the desert, allowing for better preparation and anticipation of relief. This information can help physicians optimize pregabalin treatment strategies and ensure that patients experience timely pain relief.

Dr.Camel's Conclusion

This research provides valuable insights into the use of pregabalin for neuropathic pain in patients with spinal cord injury. It highlights the potential for rapid pain relief and emphasizes the importance of understanding the timing of therapeutic effects. As researchers, we must continue to explore new and effective treatments for neuropathic pain, a condition that can significantly impact the quality of life for those affected.
Date :
  1. Date Completed 2016-04-05
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25850879

DOI: Digital Object Identifier

10.1016/j.clinthera.2015.02.028

Related Literature

SNS
PICO Info
in preparation
Languages

English

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