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Relapse analysis of irradiated patients within the HD15 trial of the German Hodgkin Study Group.

Author: BauesChristian, DietleinMarkus, EichHans Theodor, Engenhart-CabillicRita, EngertAndreas, HaverkampHeinz, HaverkampUwe, HegerfeldKira, HerfarthKlaus, KobeCarsten, KrizJan, KuhnertGeorg, LukasPeter, ReinartzGabriele, SchmidbergerHeinz, StaarSusanne

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

This study aims to determine if relapses in advanced Hodgkin lymphoma (HL) occur in the areas treated with radiation. It also investigates whether the radiation field definitions used by the German Hodgkin Study Group (GHSG) are sufficient, as there is no standardized approach for treating advanced HL across different research groups.
Paper Details　
Original Abstract of the Article :
To determine, in the setting of advanced-stage of Hodgkin lymphoma (HL), whether relapses occur in the irradiated planning target volume and whether the definition of local radiation therapy (RT) used by the German Hodgkin Study Group (GHSG) is adequate, because there is no harmonization of field an...See full text at original site
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引用元：
https://doi.org/10.1016/j.ijrobp.2015.01.048

データ提供：米国国立医学図書館（NLM）

Relapse Analysis in Hodgkin Lymphoma: Mapping the Battlefield

The treatment of Hodgkin lymphoma (HL), a complex and often challenging cancer, is akin to navigating a battlefield. This study, like a skilled military strategist, examines relapse patterns in patients with advanced-stage HL who received radiation therapy within the HD15 trial conducted by the German Hodgkin Study Group (GHSG). The authors sought to determine whether relapses occurred within the irradiated planning target volume and whether the definition of local radiation therapy used by the GHSG was adequate.

The Battlefield: Relapse Patterns in Advanced-Stage HL

The study findings, like a detailed map of the battlefield, revealed that relapses in advanced-stage HL often occurred within the irradiated planning target volume. This suggests that the definition of local radiation therapy used by the GHSG may need to be refined to ensure comprehensive coverage of the affected areas.

Strategic Planning: Refining Treatment Approaches

The study highlights the importance of meticulous planning and execution in the treatment of advanced-stage HL. It suggests that a more comprehensive approach to radiation therapy, potentially encompassing a larger irradiated volume or different radiation techniques, could improve outcomes.

Dr. Camel's Conclusion

This study, like a battle plan, underscores the need for careful planning and precise execution in the treatment of advanced-stage HL. By refining our understanding of relapse patterns and optimizing radiation therapy strategies, we can improve outcomes for patients and secure a more decisive victory against this challenging cancer.

Date :
  1. Date Completed 2015-06-16
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

25863753

DOI: Digital Object Identifier

10.1016/j.ijrobp.2015.01.048

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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