[Combination therapy of intravenous ritodrine and magnesium sulfate to inhibit premature labor].

Author: HokanishiH, IkenoueT, KamitomoM, MatsudaY

Paper Details 
Original Abstract of the Article :
Thirty-seven patients in premature labor with intact membranes were treated as follows. Ritodrine was given as a primary tocolytic agent and magnesium sulfate was added adjunctively when the uterine contractions could not be controlled even when the administration of ritodrine exceeded 250mmg/min (1...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2592821

データ提供:米国国立医学図書館(NLM)

A New Approach to Inhibiting Premature Labor: A Combination Therapy

This study delves into the intricate world of premature labor, a challenging condition for both mother and child. It's like navigating a treacherous desert with a map that leads to a safe haven. The researchers explored a novel approach to preventing premature labor, combining ritodrine and magnesium sulfate. This combination therapy aimed to prolong pregnancy and improve outcomes for both mother and baby.

Promising Results with a Combined Tocolytic Therapy

The study's findings offer a glimmer of hope in the desert of premature labor. The researchers found that the combination therapy of ritodrine and magnesium sulfate was effective in prolonging pregnancy. The study also revealed some potential side effects, suggesting the need for careful monitoring and further research. 89% of the 37 patients treated with the combination therapy achieved prolongation of pregnancy for more than 48 hours, and 68% delivered beyond 37 weeks, which are more satisfactory than those obtained with isoxsuprine treated group (122 cases). However, the study also identified some potential risks, such as an increased incidence of palpitations, hot flushes, and neonatal complications like respiratory distress.

A Balanced Approach to Tocolytic Therapy

While the findings are promising, they emphasize the need for a balanced approach to tocolytic therapy. It's like navigating the desert with caution, aware of both the potential benefits and risks. Clinicians must carefully weigh the benefits and risks of this combination therapy, considering the individual patient's circumstances. It's also crucial to monitor for potential side effects and ensure that the benefits outweigh the risks for both mother and baby.

Dr.Camel's Conclusion

The desert of pregnancy can be fraught with challenges, and premature labor is a significant threat. This study highlights the potential of combination therapy to navigate this treacherous terrain. It's a reminder that while hope and innovation offer promising solutions, careful consideration of potential risks and a personalized approach are essential. We must continue to explore new ways to improve outcomes for mothers and babies facing premature labor, always striving for a brighter future.

Date :
  1. Date Completed 1990-01-25
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2592821

DOI: Digital Object Identifier

2592821

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SNS
PICO Info
in preparation
Languages

Japanese

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