A public health risk assessment for yellow fever vaccination: a model exemplified by an outbreak in the state of São Paulo, Brazil.

Author: AmakuMarcos, BurattiniMarcelo Nascimento, CoutinhoFrancisco Antonio Bezerra, FrançaAna Cecilia Costa, LopezLuis Fernandez, MascherettiMelissa, MassadEduardo, PereiraMariza, Port-CarvalhoMarcio, RibeiroAna Freitas, SatoHelena Keico, SouzaRenato Pereira de, SpinolaRoberta, TenganCiléa

Paper Details 
Original Abstract of the Article :
We propose a method to analyse the 2009 outbreak in the region of Botucatu in the state of São Paulo (SP), Brazil, when 28 yellow fever (YF) cases were confirmed, including 11 deaths. At the time of the outbreak, the Secretary of Health of the State of São Paulo vaccinated one million people, causin...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489454/

データ提供:米国国立医学図書館(NLM)

Yellow Fever Vaccination: A Balancing Act of Risk and Benefit

Yellow fever, a viral disease transmitted by mosquitos, is a threat that can spread rapidly, like a desert sandstorm that engulfs the landscape. Vaccination is a crucial tool for preventing outbreaks, but it also carries a small risk of adverse effects. This research investigates the optimal strategy for yellow fever vaccination, balancing the risk of disease with the risk of vaccine-induced complications.

A Mathematical Approach to Vaccination Strategy

The study uses a mathematical model to analyze a yellow fever outbreak in Brazil. This model, like a map of the desert, helps to identify the optimal proportion of individuals who should be vaccinated to minimize the overall number of deaths, taking into account both the risk of yellow fever and the risk of vaccine-induced fatalities.

Navigating the Desert of Disease Prevention

The findings underscore the importance of a carefully considered vaccination strategy, like choosing the safest and most efficient route through a dangerous desert. By optimizing the proportion of individuals vaccinated, we can minimize the overall impact of the disease while minimizing the risk of adverse effects from the vaccine itself. This study provides valuable insights into the delicate balance of risk and benefit in disease prevention.

Dr. Camel's Conclusion

This research highlights the importance of a data-driven approach to yellow fever vaccination, like using a compass to navigate the complexities of disease prevention. By carefully considering the risks and benefits of vaccination, we can develop strategies that maximize public health while minimizing the potential for harm.

Date :
  1. Date Completed 2015-11-23
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

25946247

DOI: Digital Object Identifier

PMC4489454

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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