Widespread renal polycystosis induced by crizotinib.

Author: CarbonettiFrancesco, Di GirolamoMarco, MarchettiPaolo, OnestiElisa Concetta, ParisIda, SocciarelliFabio

Paper Details 
Original Abstract of the Article :
With the widespread availability of biological antitumor drugs, the current scene of chemotherapies is changing. New chemotherapy agents, such as crizotinib, an inhibitor of anaplastic lymphoma kinase (ALK) and ROS1, usually used in pretreated advanced ALK-positive non-small-cell lung carcinoma, are...See full text at original site
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引用元:
https://doi.org/10.5301/tj.5000338

データ提供:米国国立医学図書館(NLM)

Crizotinib: A Double-Edged Sword in Cancer Treatment

The field of cancer therapy is constantly evolving, with new drugs like crizotinib offering hope for patients with advanced non-small-cell lung carcinoma. However, this research highlights a concerning side effect: widespread renal polycystosis, a condition where multiple cysts develop in the kidneys. It's like a beautiful desert flower with a poisonous sting - a potential complication that requires careful monitoring and management.

Managing the Risks: A Balancing Act

This case study serves as a reminder that even with the promise of new treatments, careful monitoring and management are essential. While crizotinib can be effective in combating cancer, the researchers caution about the potential for this unexpected side effect. This underscores the need for physicians to be aware of these potential risks and be prepared to respond appropriately. It's like navigating a treacherous oasis; understanding the potential dangers is crucial for survival.

Staying Informed: A Crucial Step in Healthcare

This research highlights the importance of staying informed about the potential side effects of new medications, even those offering hope for serious conditions. It emphasizes the need for careful communication between physicians and patients, ensuring that all potential risks and benefits are clearly understood. It's like reading the desert map carefully before embarking on a journey; knowing the lay of the land can make all the difference.

Dr.Camel's Conclusion

This case study underscores the importance of understanding the full spectrum of a treatment's effects, both beneficial and detrimental. It serves as a reminder that even with promising advances in medicine, vigilance and open communication are crucial for navigating the complexities of healthcare. It's a journey we must undertake with both cautious optimism and a keen eye for the details that can shape our health outcomes.

Date :
  1. Date Completed 2015-10-19
  2. Date Revised 2019-02-21
Further Info :

Pubmed ID

25953441

DOI: Digital Object Identifier

10.5301/tj.5000338

Related Literature

SNS
PICO Info
in preparation
Languages

English

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