Safety, tolerability, and immunogenicity of zoster vaccine in subjects on chronic/maintenance corticosteroids.

Author: CollKathleen E, FisherChester L, LiXiaoming, ParrinoJanie, RussellAmy F, SchliengerKatia, SilberJeffrey L, SpielerWolfgang, StekJon E, SuShu-Chih, XuJin

Paper Details 
Original Abstract of the Article :
This randomized, placebo-controlled study assessed the safety, tolerability, and immunogenicity of live virus zoster vaccine (ZV) in individuals receiving chronic/maintenance systemic corticosteroid therapy (daily dose equivalent of 5-20mg prednisone) for ≥2 weeks prior to vaccination and ≥6 weeks p...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.vaccine.2015.04.090

データ提供:米国国立医学図書館(NLM)

Zoster Vaccine: Safety and Immunogenicity in Corticosteroid Users

Vaccines are like protective shields in the desert, helping us ward off potential threats to our health. This research explores the safety and efficacy of the zoster vaccine in individuals receiving chronic corticosteroid therapy, a common treatment for a variety of conditions. It's like navigating a desert landscape, seeking to ensure the safety and effectiveness of a vital medical tool.

The research evaluated the safety, tolerability, and immunogenicity of the zoster vaccine in individuals receiving chronic corticosteroid therapy. The study found that the vaccine was generally safe and well-tolerated in this population, suggesting it can be a valuable tool for protecting these individuals against shingles.

Protecting Against Shingles: A Key Consideration

This study highlights the importance of protecting individuals receiving chronic corticosteroid therapy from shingles, a potentially painful and debilitating condition. It's like recognizing the need for a sturdy camel to navigate a harsh desert environment - a vital consideration for ensuring well-being. The study provides evidence for the safety and efficacy of the zoster vaccine in this population.

The Importance of Personalized Vaccination Strategies

This research emphasizes the need for personalized vaccination strategies, taking into account individual patient factors. It's like choosing the right gear for a desert trek - you need to consider the specific conditions and the needs of the traveler. The study suggests that the zoster vaccine can be a valuable tool for protecting individuals receiving corticosteroid therapy, but careful evaluation and individualized decision-making are essential.

Dr. Camel's Conclusion

This research underscores the importance of vaccination, even for individuals receiving chronic corticosteroid therapy. It's like carrying a compass and a supply of water in the desert - essential tools for navigating potential health challenges. By understanding the safety and efficacy of vaccines in this population, healthcare professionals can develop personalized vaccination strategies to improve health outcomes and protect individuals from potentially debilitating conditions like shingles.

Date :
  1. Date Completed 2016-02-25
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

25964168

DOI: Digital Object Identifier

10.1016/j.vaccine.2015.04.090

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.