Beyond COX-inhibition: 'side-effects' of ibuprofen on neoplastic development and progression.

Author: JordanPeter, MatosPaulo

Paper Details 
Original Abstract of the Article :
Ibuprofen is a non-steroidal anti-inflammatory drug of generalized use with over-the-counter availability. Population-based studies have provided evidence that its long-term use is associated with a 30-60% decrease in the risk of developing major types of cancer. Initially, the underlying molecular ...See full text at original site
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引用元:
https://doi.org/10.2174/1381612821666150514104608

データ提供:米国国立医学図書館(NLM)

Ibuprofen: More Than Just a Pain Reliever

Ibuprofen, a familiar companion in our medicine cabinets, has long been known for its pain-relieving properties. However, this study explores the vast desert of ibuprofen's potential, revealing its remarkable ability to impact cancer development and progression. Researchers have unearthed evidence suggesting that long-term use of ibuprofen may significantly reduce the risk of developing various cancers, highlighting its versatility and unexpected benefits.

A Multifaceted Guardian Against Cancer

While ibuprofen's COX-2-inhibiting effects are well-established, this study delves deeper, revealing a multifaceted role in cancer prevention. The researchers discovered that ibuprofen's impact extends beyond COX-2 inhibition, influencing gene expression, alternative splicing, and various cell cycle- and apoptosis-regulating pathways. It's like a wise desert traveler, possessing a diverse toolkit for navigating the treacherous landscape of cancer development.

A Dose of Prevention

This research offers valuable insight into the potential benefits of ibuprofen, but it's crucial to consult with your healthcare provider before making any significant changes to your medication regimen. Ibuprofen, like any medication, may have side effects, and its use should be carefully considered. Remember, the desert of health requires responsible navigation!

Dr.Camel's Conclusion

Ibuprofen, a common desert remedy, may hold a hidden secret – a powerful ability to influence cancer development. While more research is needed, this study suggests that ibuprofen's impact extends beyond pain relief, offering a glimmer of hope for future cancer prevention strategies.

Date :
  1. Date Completed 2016-03-01
  2. Date Revised 2019-07-28
Further Info :

Pubmed ID

26004413

DOI: Digital Object Identifier

10.2174/1381612821666150514104608

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SNS
PICO Info
in preparation
Languages

English

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