Effects of Miglitol, Acarbose, and Sitagliptin on Plasma Insulin and Gut Peptides in Type 2 Diabetes Mellitus: A Crossover Study.

Author: NagamineKazuhiro, NakazatoMasamitsu, SakodaHideyuki, TsubouchiChikako, TsuchimochiWakaba, UenoHiroaki, WangHong-Wei, YamashitaEiichiro

Paper Details 
Original Abstract of the Article :
Both dipeptidyl peptidase-4 inhibitors and α-glucosidase inhibitors (α-GI) have been reported to change the incretin and insulin secretion. To examine the effects of acarbose, miglitol, and sitagliptin on glucose metabolism and secretion of gut peptides, we conducted a crossover study in patients wi...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478179/

データ提供:米国国立医学図書館(NLM)

The Intricate Dance of Diabetes Medications

The realm of [diabetes management] is a desert of complexities, where different medications interact in intricate ways. This research explores the [effects of miglitol, acarbose, and sitagliptin] on [plasma insulin and gut peptides] in [patients with type 2 diabetes mellitus (T2DM)]. The study employed a [crossover study] design to investigate the [impact of these medications] on [glucose metabolism and gut peptide secretion].

Understanding the Impact of Diabetes Medications

The research highlights the [complex interplay] between [diabetes medications] and [glucose metabolism]. The study found that [miglitol, acarbose, and sitagliptin] had [distinct effects] on [plasma insulin and gut peptide levels]. It's like observing the intricate dance of sand dunes – each medication interacts with the others and the body's natural processes in unique ways.

Optimizing Diabetes Management

This research emphasizes the importance of [individualized treatment approaches] for [patients with type 2 diabetes mellitus]. It suggests that [carefully selecting medications] and [monitoring their effects] can help optimize treatment outcomes and improve patient well-being. It's like finding the right path through a desert – the right medication combination can help patients achieve better control of their diabetes.

Dr.Camel's Conclusion

This research provides a valuable glimpse into the [complex world of diabetes management]. It underscores the importance of [understanding the effects of medications] and [personalizing treatment plans] to ensure optimal outcomes for patients.

Date :
  1. Date Completed 2015-06-24
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

26055217

DOI: Digital Object Identifier

PMC4478179

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Languages

English

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