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Comparison of renal safety and efficacy of telbivudine, entecavir and tenofovir treatment in chronic hepatitis B patients: real world experience.

Author: ChangK-C, ChenC-H, ChiuK-W, ChouY-P, HuT-H, HungC-H, LeeC-M, LinM-T, LuS-N, TsaiM-C, TsengP-L, WangJ-H, YenY-H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Tenofovir may cause renal function deterioration, while telbivudine is associated with a high rate of virological breakthrough. Entecavir appears to be the best choice among these three agents with low rates of virological breakthrough and preservation of renal function.
Paper Details　
Original Abstract of the Article :
This study aims to assess the nephrotoxicity and efficacy of tenofovir disoproxil fumarate (tenofovir), telbivudine and entecavir. A retrospective study of 587 patients with chronic hepatitis B treated with tenofovir (n = 170), telbivudine (n = 184) and entecavir (n = 233) for at least 1 year. Renal...See full text at original site
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引用元：
https://doi.org/10.1016/j.cmi.2015.05.035

データ提供：米国国立医学図書館（NLM）

Hepatitis B Treatment: A Comparison of Medications

This study delves into the treatment of chronic hepatitis B, a viral infection that affects the liver. Imagine a camel trying to find a source of clean water in a desert oasis. This study compares the safety and effectiveness of three medications commonly used to treat chronic hepatitis B, namely tenofovir, telbivudine, and entecavir. Researchers analyzed real-world data to assess the impact of these medications on kidney function and their ability to suppress the virus. The study provides insights into the relative advantages and disadvantages of each medication, helping healthcare providers make informed decisions about the best treatment option for their patients.

Navigating the Treatment Options

This research offers a valuable comparison of different medications used to treat chronic hepatitis B, helping healthcare providers navigate the complex landscape of treatment options. It's like a camel carefully choosing its path through the desert, seeking the best route to reach its destination. The study provides important information about the potential risks and benefits of each medication, allowing healthcare providers to tailor treatment to individual patients' needs.

Personalized Care

This study emphasizes the importance of personalized care in managing chronic hepatitis B. It's essential to work closely with your healthcare provider to find the best medication and treatment plan for your unique situation. Just as a camel needs to adapt to the changing conditions of the desert, patients with chronic hepatitis B need to be proactive in managing their condition.

Dr. Camel's Conclusion

This study provides a valuable comparison of different medications used to treat chronic hepatitis B, helping healthcare providers navigate the complex landscape of treatment options. It highlights the importance of personalized care and underscores the need for open communication between patients and healthcare providers to ensure the best possible outcomes for managing this condition.
Date :
  1. Date Completed 2016-12-13
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

26055419

DOI: Digital Object Identifier

10.1016/j.cmi.2015.05.035

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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