Comparative safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis.

Author: AntonyJesmin, AshoorHuda, BlondalErik, HemmelgarnBrenda R, HoJoanne, HuttonBrian, IvoryJohn, KhanPaul A, MacDonaldHeather, MoherDavid, MrklasKelly, NgCarmen, ReynenEmily, RobsonReid, SoobiahCharlene, StrausSharon E, StriflerLisa, TriccoAndrea C, VafaeiAfshin, VeronikiAreti A

Paper Details 
Original Abstract of the Article :
BACKGROUND: Serotonin (5-HT3) receptor antagonists are commonly used to decrease nausea and vomiting for surgery patients, but these agents may be harmful. We conducted a systematic review on the comparative safety of 5-HT3 receptor antagonists. METHODS: Searches were done in MEDLINE, Embase, and t...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472408/

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Antiemetic Medications

Surgery can be a stressful experience, sometimes accompanied by nausea and vomiting, like a desert traveler encountering a sudden sandstorm. This research explores the safety of different medications used to prevent these side effects.

The study systematically reviewed and analyzed data from multiple studies comparing the safety of different serotonin (5-HT3) receptor antagonists, commonly used antiemetic medications. It's like mapping the different paths through a desert, assessing the risks and benefits of each route.

The study found that granisetron plus dexamethasone was associated with a significantly higher risk of arrhythmia compared to other antiemetic medications. This is like discovering a path through a desert that's prone to flash floods, potentially posing a danger to travelers.

Choosing the Right Path

This research highlights the importance of carefully considering the potential risks and benefits of different medications. It's like choosing a safe and reliable path through a desert, minimizing the chances of encountering unexpected dangers.

A Guide for Safe Travel

The study provides valuable information for healthcare professionals, guiding them in choosing the most appropriate antiemetic medications for their patients. It's like having a knowledgeable desert guide, who can identify the safest and most effective routes for a successful journey.

Dr. Camel's Conclusion

This research serves as a reminder that even in the realm of medication, there are risks and benefits to consider. It's like navigating a desert, where each path has its own unique challenges and opportunities.

Date :
  1. Date Completed 2015-10-16
  2. Date Revised 2020-05-11
Further Info :

Pubmed ID

26084332

DOI: Digital Object Identifier

PMC4472408

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Languages

English

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