Paper Details

  1. Home
  2. Paper Details

The Combined Impact of Exhaled Nitric Oxide and Sputum Eosinophils Monitoring in Asthma Treatment: A Prospective Cohort Study.

Author: MalerbaMario, MontuschiPaolo, OliviniAlessia, RadaeliAlessandro, RagnoliBeatrice, RicciardoloFabio

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared the effectiveness of asthma control using fraction of exhaled nitric oxide (FENO) and sputum eosinophils versus a clinical score. The intervention group had a significant reduction in exacerbation rate by 73% at 12 months and 84% at 24 months, compared to the control group. The intervention group also had a significantly lower symptom score at 24 months. Both groups had an increase in inhaled corticosteroid (ICS) dose, but there was no difference between groups.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Inhaled corticosteroids (ICS) treatment for asthma control is generally focused on lung function and symptoms, but inadequately correlated with airway inflammation. OBJECTIVE: To compare asthma control in a group of patients whose treatment was based on fraction of exhaled nitric oxide ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.2174/1871524915666150710123415

データ提供：米国国立医学図書館（NLM）

Asthma Management: A Precision Approach

Asthma management often focuses on lung function and symptoms, but a precision approach that considers underlying airway inflammation is crucial for optimal control. This study evaluated the effectiveness of monitoring exhaled nitric oxide (FENO) and sputum eosinophils in guiding asthma treatment. Researchers found that using these biomarkers to adjust treatment led to better asthma control, with fewer exacerbations and improved symptom scores compared to traditional clinical-score-based management. It's like having a compass and a map in the desert of asthma, guiding the patient toward a path of improved health.

A New Path for Asthma Management

This study suggests that monitoring FENO and sputum eosinophils can enhance asthma management, leading to improved patient outcomes. This is like discovering a hidden oasis in the desert of asthma, offering a more effective and targeted approach to treatment.

Personalized Asthma Care

This study emphasizes the importance of personalized asthma care, where treatment is tailored to the individual patient's needs based on their specific biomarkers. It's like providing a customized map for each traveler in the desert of asthma, guiding them toward a path of optimal well-being.

Dr.Camel's Conclusion

This study provides evidence that monitoring FENO and sputum eosinophils can improve asthma management, leading to better control and reduced exacerbations. It underscores the importance of a precision approach to asthma care, where treatment is tailored to the individual patient's needs. This is a journey through the desert of asthma, and this study offers a potential oasis of improved management and control.

Date :
  1. Date Completed 2016-09-05
  2. Date Revised 2019-07-28
Further Info :

Pubmed ID

26166613

DOI: Digital Object Identifier

10.2174/1871524915666150710123415

Related Literature

Article Analysis
・Effective treatment of asthma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.