Paper Details

  1. Home
  2. Paper Details

Efficacy of Kisspeptin-54 to Trigger Oocyte Maturation in Women at High Risk of Ovarian Hyperstimulation Syndrome (OHSS) During In Vitro Fertilization (IVF) Therapy.

Author: AbbaraAli, AshbyDeborah A, BloomStephen R, BuckleyAdam, ChristopoulosGeorgios, ComninosAlexander N, DhilloWaljit S, Izzi-EngbeayaChioma, JayasenaChanna N, LaveryStuart A, NarayanaswamyShakunthala, NijherGurjinder M K, PetersDeborah, PragueJulia K, RatnasabapathyRisheka, SalimRehan, SzigetiMatyas, TrewGeoffrey H

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A phase 2, multi-dose, open-label, randomized clinical trial of 60 women undergoing IVF treatment at high risk of developing OHSS found that kisspeptin-54 is a promising approach to effectively and safely trigger oocyte maturation.
Paper Details　
Original Abstract of the Article :
CONTEXT: In vitro fertilization (IVF) treatment is an effective therapy for infertility, but can result in the potentially life-threatening complication, ovarian hyperstimulation syndrome (OHSS). OBJECTIVE: This study aimed to investigate whether kisspeptin-54 can be used to effectively and safely ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570165/

データ提供：米国国立医学図書館（NLM）

Kisspeptin-54: A New Oasis in the Desert of IVF

Imagine a desert where the delicate balance of life is disrupted, making it difficult to cultivate new growth. That's what infertility can be like, a condition that can make it challenging to conceive naturally. This study explores the potential of kisspeptin-54, a hormone, to trigger oocyte maturation in women undergoing in vitro fertilization (IVF) treatment. The researchers are like skilled gardeners, seeking to cultivate new life in the challenging landscape of infertility.

A Promising New Tool for IVF Treatment

The researchers are like innovative desert farmers, exploring new ways to cultivate life in the desert. Their research reveals that kisspeptin-54 can effectively and safely trigger oocyte maturation in women undergoing IVF treatment. The results are promising, showing high rates of oocyte maturation and pregnancy.

Cultivating Hope in the Desert of Infertility

For couples struggling with infertility, the journey to parenthood can feel like navigating a vast and challenging desert. This research offers a glimmer of hope, suggesting that kisspeptin-54 could be a valuable tool for IVF treatment, increasing the chances of conception and creating a more fertile landscape.

Dr.Camel's Conclusion

This study is a reminder that even in the seemingly barren desert of infertility, there can be oases of hope. Kisspeptin-54 emerges as a promising new tool for IVF treatment, offering a chance for couples to cultivate their dreams of parenthood.

Date :
  1. Date Completed 2015-11-24
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

26192876

DOI: Digital Object Identifier

PMC4570165

Related Literature

Article Analysis
・Effective treatment of infertility
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.