D-penicillamine Induced Degenerative Dermopathy.

Author: BehariMadhuri, ChatterjeePriti, JainNaresh, KhandpurSujay, SinglaShweta

Paper Details 
Original Abstract of the Article :
D-penicillamine interferes with elastin and collagen metabolism and produces several cutaneous and multi-systemic side-effects. We present two cases of Wilson's disease who on long-term penicillamine therapy developed drug-induced degenerative dermopathy manifesting as skin fragility over pressure s...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533546/

データ提供:米国国立医学図書館(NLM)

D-penicillamine: A Double-Edged Sword for Wilson's Disease

Wilson's disease, a rare genetic disorder, often requires medications like D-penicillamine to manage its symptoms. This research highlights the potential side effects of long-term D-penicillamine therapy, specifically focusing on its impact on the skin. The study presents two cases where patients with Wilson's disease developed degenerative dermopathy, characterized by skin fragility and cutis laxa-like changes. It's like exploring the hidden dangers of a beautiful but treacherous desert landscape, where seemingly safe paths can lead to unexpected consequences.

Navigating the Risks of D-penicillamine Therapy

This study serves as a cautionary reminder of the potential risks associated with long-term D-penicillamine therapy. It emphasizes the need for careful monitoring and early detection of any adverse effects, including skin changes. The study underscores the importance of individualized treatment plans and the need to weigh the potential benefits of therapy against the risks involved.

Maintaining Skin Health During D-penicillamine Treatment

Patients undergoing D-penicillamine therapy should be aware of the potential for skin complications. Close monitoring by healthcare providers and early intervention can help to mitigate these risks and prevent further complications. It's like using a skilled guide to navigate the desert, ensuring that potential hazards are identified and addressed promptly.

Dr.Camel's Conclusion

This study emphasizes the importance of understanding the potential side effects of any medication, even those used to treat serious conditions. It highlights the need for careful monitoring and proactive care to ensure the safety and well-being of patients.

Date :
  1. Date Completed 2015-08-20
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

26288416

DOI: Digital Object Identifier

PMC4533546

Related Literature

SNS
PICO Info
in preparation
Languages

English

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