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Dapsone in the treatment of pemphigus vulgaris: adverse effects and its importance as a corticosteroid sparing agent.
Author: Azulay-AbulafiaLuna, Bernardes FilhoFred, HezelJanaína, KacBernard Kawa, PerettiMurilo Calvo, QuaresmaMaria Victória
Original Abstract of the Article :
Pemphigus vulgaris is an autoimmune disease characterized by suprabasal blisters with acantholysis, which has a fatal course in a large number of untreated patients. Systemic corticosteroid therapy is considered first-line therapy. Adjuvant treatment with the goal of sparing corticosteroids include,...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540507/
データ提供:米国国立医学図書館(NLM)
Dapsone: A Corticosteroid-Sparing Agent for Pemphigus Vulgaris
This study examines the use of dapsone, an anti-inflammatory drug, as a corticosteroid-sparing agent in the treatment of pemphigus vulgaris, a severe autoimmune blistering skin disease. The study presents a case report of a patient with pemphigus vulgaris who initially received suboptimal doses of prednisone, a corticosteroid, but experienced drug-induced hepatitis after the introduction of dapsone. The study highlights the potential benefits of dapsone in reducing corticosteroid dependence but emphasizes the need for careful monitoring and management of potential adverse effects.Balancing the Scales: Dapsone and Corticosteroids
This study underscores the complex interplay between different medications in the treatment of pemphigus vulgaris. While dapsone may offer a way to reduce reliance on corticosteroids, it's essential to carefully monitor for potential side effects. It's like a camel navigating a narrow path between two towering sand dunes, requiring careful attention to maintain balance and avoid falling into the depths.Beyond the Sands: Exploring Personalized Treatment Approaches
This research emphasizes the importance of individualized treatment approaches for patients with pemphigus vulgaris. The optimal therapeutic strategy may vary depending on individual factors, including disease severity, response to medication, and potential risks. It's like a camel adapting its strategy to the changing terrain of the desert, finding the most suitable path to reach its destination.Dr.Camel's Conclusion
This study highlights the ongoing challenge of finding effective and safe treatments for pemphigus vulgaris. While dapsone offers a potential corticosteroid-sparing option, careful monitoring and individualized treatment strategies are crucial. It's a reminder that the search for solutions continues, just as a camel tirelessly traverses the desert in search of a hidden oasis.Date :
- Date Completed 2016-01-12
- Date Revised 2019-11-20
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