Novel levocetirizine HCl tablets with enhanced palatability: synergistic effect of combining taste modifiers and effervescence technique.

Author: LabibGihan S

Paper Details 
Original Abstract of the Article :
Levocetirizine HCl, a second-generation piperazine derivative and H1-selective antihistaminic agent, possesses few side effects. The first objective of the study was to compare and evaluate the taste-masking effect of different ratios of 2-hydroxypropyl-β-cyclodextrin and mannitol on levocetirizine ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567242/

データ提供:米国国立医学図書館(NLM)

Levocetirizine HCl: Taming the Taste Buds

Levocetirizine HCl, a common allergy medication, can be a challenge for patients due to its unpleasant taste. This study aims to find a way to make this medication more palatable, exploring different combinations of taste modifiers and effervescence techniques.

The study tested various combinations of 2-hydroxypropyl-β-cyclodextrin and mannitol to create taste-masked levocetirizine HCl. The researchers then explored the potential of preparing effervescent tablets using the best-chosen taste-masked blends. This would allow patients to choose between orodispersible tablets (dissolving in the mouth) or water-soluble effervescent tablets.

Enhanced Palatability: A Patient-Centric Approach

This study aims to improve patient compliance by making medication more palatable. By addressing a common challenge with levocetirizine HCl, this research could lead to better medication adherence and ultimately, better health outcomes. It's like finding a hidden oasis in the desert of unpleasant medications, making the journey a little bit more enjoyable.

Medication Compliance: A Matter of Taste

Medication adherence is crucial for effective treatment. This study highlights the importance of considering patient preferences and making medications more palatable. A little bit of sweetness can go a long way, making the journey of medication taking a little less bitter.

Dr. Camel's Conclusion

This study reminds us that even in the vast desert of medications, a little bit of sweetness can make a big difference. Finding ways to improve medication palatability is a crucial step towards better patient compliance and improved health outcomes. It's like finding a hidden spring in the desert, offering a refreshing respite from the harshness of medications.

Date :
  1. Date Completed 2016-07-12
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

26379426

DOI: Digital Object Identifier

PMC4567242

SNS
PICO Info
in preparation
Languages

English

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