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Hyaluronic acid and other conservative treatment options for osteoarthritis of the ankle.

Author: HofstadCheriel J, KerkhoffsGino M M J, WitteveenAngelique G H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

There is insufficient data to create a synthesis of the evidence for future guidelines for ankle osteoarthritis (OA). Simple analgesics are a reasonable first step to treat ankle OA, and HA can be conditionally recommended if patients have an inadequate response to simple analgesics.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The cause of ankle osteoarthritis (OA) is usually trauma. Patients are relatively young, since ankle trauma occurs at a relatively young age. Several conservative treatment options are available, evidence of the benefits and harms of these options are lacking. OBJECTIVES: To assess the ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254328/

データ提供：米国国立医学図書館（NLM）

Hyaluronic Acid: A Potential Oasis in the Desert of Ankle Osteoarthritis

The research examines the effectiveness of [Hyaluronic Acid (HA)] as a conservative treatment for ankle osteoarthritis (OA), a condition that can significantly impact mobility and quality of life. The study, a systematic review of randomized controlled trials, assesses the benefits and harms of HA injections compared to other conservative treatments, including placebo, exercise therapy, and botulinum toxin. The research provides a comprehensive overview of the available evidence regarding the use of HA in the management of ankle OA, offering valuable insights for clinicians and patients seeking effective treatment options.

Hyaluronic Acid: A Mixed Bag of Results

The research presents a mixed bag of results regarding the effectiveness of HA in treating ankle OA. While the study found some evidence that HA may offer a modest improvement in pain and function compared to placebo, the overall quality of evidence was considered low due to limitations in the studies included. The study also found inconclusive results when comparing HA to other conservative treatments, suggesting that further research is needed to determine the optimal treatment approach for ankle OA.

Hyaluronic Acid: A Potential Option, But More Research is Needed

This research highlights the need for further research to clarify the role of HA in the management of ankle OA. While some evidence suggests a potential benefit, the study emphasizes the limitations of current research and the need for larger, well-designed studies to provide definitive answers. This research encourages a cautious approach to the use of HA for ankle OA, recommending its use as a potential option if patients fail to respond to simpler analgesic approaches.

Dr.Camel's Conclusion

The desert offers a harsh landscape, and ankle OA can feel similarly daunting. This research, while providing some insights into the potential benefits of HA, underscores the need for a comprehensive approach to managing this condition. It's important to remember that the desert, despite its challenges, also offers hidden oases of hope. This research encourages a continued search for effective and well-tolerated treatments for ankle OA, ultimately aiming to improve the quality of life for individuals affected by this debilitating condition.

Date :
  1. Date Completed 2016-04-07
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

26475434

DOI: Digital Object Identifier

PMC9254328

Related Literature

Article Analysis
・Effective treatment of osteoarthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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