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[The effects of captopril and metoprolol on blood pressure and side effects in patients with mild to moderate hypertension].

Author: KornerupH J, KorsagerS

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Captopril + a diuretic is as effective as metoprolol + a diuretic in treating mild to moderate hypertension. In a randomized study of 76 patients, satisfactory blood pressure regulation and wellbeing were achieved in 29 patients in the captopril group and 23 patients in the metoprolol group. Side effects were similar between the two groups, with 14 side effects in 8 patients in the captopril group and 23 side effects in 15 patients in the metoprolol group.
Paper Details　
Original Abstract of the Article :
A material of 76 patients from general practice treated with diuretics for mild to moderate hypertension were randomized to supplementary treatment with captopril (39 patients) and metoprolol (37 patients), respectively, on account of diastolic blood pressure greater than or equal to 95 mmHg. Satisf...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2652842

データ提供：米国国立医学図書館（NLM）

Captopril vs. Metoprolol: A Comparative Study in Hypertension

This study takes us on a journey through the landscape of hypertension, exploring the effectiveness of two commonly used antihypertensive medications, captopril and metoprolol. It's like comparing two different paths in the desert, each leading to a different oasis of blood pressure control. The researchers investigated the effectiveness of these medications in managing mild to moderate hypertension, comparing their effects on blood pressure and side effects.

Similar Efficacy but Distinctive Side Effects

The study found that both captopril and metoprolol, when combined with diuretics, effectively controlled blood pressure in patients with mild to moderate hypertension. However, there was a slight difference in the number of side effects reported. While both medications had similar side effect profiles, metoprolol seemed to be associated with a slightly higher incidence of adverse events.

Finding the Right Treatment for Each Patient

This research highlights the importance of individualizing treatment approaches in hypertension management. It emphasizes that the choice of medication should be tailored to the patient's specific needs and risk factors, taking into account both the efficacy and the potential side effects.

Dr.Camel's Conclusion

This study sheds light on the effectiveness of both captopril and metoprolol in managing hypertension. It provides a valuable comparison of their efficacy and side effect profiles, reminding us that there is no one-size-fits-all approach to hypertension treatment. It's a reminder that each patient's journey through the desert of hypertension requires a personalized approach, with careful consideration of both the benefits and the risks of different treatment options.

Date :
  1. Date Completed 1989-05-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2652842

DOI: Digital Object Identifier

2652842

SNS
PICO Info
in preparation
Languages

Danish

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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