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Comparison of the intraocular pressure-lowering effect and safety of brimonidine/timolol fixed combination and 0.5% timolol in normal-tension glaucoma patients.
Author: KimChan Yun, KimHwang Ki, KimJoon Mo, KimTae-Woo, ParkKi Ho
Original Abstract of the Article :
PURPOSE: To compare the therapeutic efficacy and safety of brimonidine/timolol fixed-combination (BTFC) and 0.5% timolol ophthalmic solution in normal-tension glaucoma (NTG) patients. METHODS: This was a multi-institution, randomized, active-controlled, open-label, parallel-group study. After a ful...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1007/s10384-015-0420-2
データ提供:米国国立医学図書館(NLM)
Brimonidine/Timolol Fixed Combination vs. Timolol: A Showdown in Normal-Tension Glaucoma
In the realm of [normal-tension glaucoma (NTG)], where delicate eye pressure regulation is key, researchers sought to find the most effective treatment. This study presents a head-to-head comparison of [brimonidine/timolol fixed-combination (BTFC) and 0.5% timolol ophthalmic solution], two commonly used medications. The researchers embarked on a clinical trial, akin to a desert expedition, to meticulously assess the efficacy and safety of these drugs.
BTFC Emerges as a Clear Winner
The study reveals that BTFC is a more potent IOP-lowering agent compared to 0.5% timolol. A significantly higher percentage of patients in the BTFC group experienced a greater than 20% reduction in IOP after both 4 and 12 weeks. This suggests that BTFC may be a more effective option for managing NTG.
Keeping NTG at Bay: A New Weapon in the Arsenal
The findings of this study could lead to improved management of NTG, a condition that affects millions worldwide. Just as a desert traveler relies on a reliable compass, individuals with NTG need effective treatments to navigate their journey towards healthy vision.
Dr. Camel's Conclusion
This research serves as a reminder that in the field of medicine, like a desert landscape, there are always new discoveries to be made. BTFC emerges as a potential game-changer for NTG, providing a new weapon in the fight against this debilitating eye condition.
Date :
- Date Completed 2016-10-14
- Date Revised 2018-11-13
Further Info :
Related Literature
English
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