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Zinc compounds, a new treatment in peptic ulcer.

Author: BulbenaO, EscolarG

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Zinc acexamate (ZAC) is an effective treatment for peptic ulcer disease. ZAC protects against ulcers in several experimental models and reduces gastric acid output. It also enhances mucosal protection factors by increasing mucus secretion, inhibiting H+ retrodiffusion and improving microcirculation. ZAC is effective in both acute and maintenance treatment of gastric and duodenal ulcers, and clinical trials have shown it to be effective in reducing the inflammatory processes associated with ulcer healing. Side effects are minimal, affecting less than 2% of treated patients.
Paper Details　
Original Abstract of the Article :
Effects of zinc in gastric ulcer have been reviewed through investigations carried out on zinc acexamate (ZAC). ZAC is an organic compound that has been shown to possess an experimental antiulcer effect and a wide therapeutic index, making it a useful drug in the treatment of peptic ulcer disease. Z...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/2661183

データ提供：米国国立医学図書館（NLM）

Zinc Compounds: A New Frontier in Peptic Ulcer Treatment

This research explores the potential of zinc compounds, particularly zinc acexamate (ZAC), in the treatment of peptic ulcers. The study, based on a review of experimental and clinical data, examines the effects of ZAC on gastric ulceration and its mechanisms of action. The researchers meticulously analyzed the antiulcer properties of ZAC, considering its effects on gastric acid secretion, mucosal protection, and ulcer healing. Their findings suggest that ZAC could offer a promising therapeutic option for managing peptic ulcers, potentially improving treatment outcomes and patient well-being.

Zinc Acexamate: A Multifaceted Approach to Ulcer Healing

The study observed that ZAC effectively protected against ulceration in various experimental models. The researchers found that ZAC reduced gastric acid output, enhanced mucosal protection factors, and promoted ulcer healing. Their findings suggest that ZAC could offer a multifaceted approach to treating peptic ulcers, targeting both acid suppression and mucosal defense mechanisms.

Navigating the Deserts of Digestive Distress

This research provides valuable insights into the potential of zinc compounds in managing peptic ulcers. The study’s findings on ZAC highlight the importance of exploring novel therapeutic approaches for addressing digestive distress and improving patient outcomes. It’s like finding a hidden oasis of healing in the desert of peptic ulcer discomfort.

Dr. Camel's Conclusion

This study offers a compelling exploration of zinc compounds, particularly ZAC, as a potential therapeutic agent for peptic ulcers. The findings suggest that ZAC could offer a valuable tool for managing these common gastrointestinal conditions, potentially improving treatment outcomes and patient well-being. It’s like discovering a new and effective camel caravan for navigating the desert of digestive distress.
Date :
  1. Date Completed 1989-08-10
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

2661183

DOI: Digital Object Identifier

2661183

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Languages

English

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