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Pain exposure physical therapy (PEPT) compared to conventional treatment in complex regional pain syndrome type 1: a randomised controlled trial.

Author: BarnhoornKarlijn J, FrölkeJan Paul M, GroenewoudHans, KlompFrank P, Nijhuis-van der SandenMaria W G, SamwelHan, StaalJ Bart, van DongenRobert T M, van de MeentHenk

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This randomized controlled trial compared the effectiveness of pain exposure physical therapy (PEPT) with conventional treatment in patients with complex regional pain syndrome type 1 (CRPS-1). While both treatments showed clinically relevant improvements in pain, there was no significant difference between groups. Participants in the PEPT group experienced greater improvement in active range of motion. The per protocol analysis showed larger and significant between-group effects on several outcomes, suggesting that further research on PEPT is warranted.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To compare the effectiveness of pain exposure physical therapy (PEPT) with conventional treatment in patients with complex regional pain syndrome type 1 (CRPS-1) in a randomised controlled trial with a blinded assessor. SETTING: The study was conducted at a level 1 trauma centre in the N...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679993/

データ提供：米国国立医学図書館（NLM）

PEPT: A New Approach to Complex Regional Pain Syndrome (CRPS)

Complex regional pain syndrome (CRPS) is a chronic pain condition that can significantly impact an individual's quality of life. This study explores the effectiveness of a new treatment approach, pain exposure physical therapy (PEPT), for patients with CRPS type 1 (CRPS-1). This research area is critical as it seeks to identify innovative strategies for managing a complex and often debilitating condition.

Comparing PEPT with Conventional Treatment

The study, a randomized controlled trial, compared the outcomes of 56 patients with CRPS-1 who received either PEPT or conventional treatment. The researchers meticulously evaluated various parameters, including pain levels, range of motion, and functional mobility. While the intention-to-treat analysis revealed no significant between-group differences, the per-protocol analysis indicated that PEPT led to greater improvements in several areas, including range of motion. These findings suggest that PEPT might hold promise for managing CRPS-1, offering a potential alternative to conventional treatment strategies.

Exploring Potential Benefits of PEPT

This research suggests that PEPT, like a well-worn path through the desert of chronic pain, could lead to significant improvements in functional mobility and pain relief for patients with CRPS-1. While further research is needed to confirm its efficacy, PEPT offers a potential alternative to conventional treatment approaches, opening new possibilities for managing this challenging condition. The study's findings are like a refreshing oasis in the desert of CRPS-1 research, offering hope for a brighter future for patients.

Dr.Camel's Conclusion

CRPS, like a scorching desert sun, can cause intense and unrelenting pain. However, this research suggests that PEPT, like a cool breeze in the desert, could bring relief and improve the quality of life for those struggling with this challenging condition.

Date :
  1. Date Completed 2016-09-19
  2. Date Revised 2019-02-02
Further Info :

Pubmed ID

26628523

DOI: Digital Object Identifier

PMC4679993

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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