Paper Details 
Original Abstract of the Article :
Antimuscarinics are the principal pharmacological treatment for overactive bladder (OAB), but frequently give rise to anticholinergic side effects, such as dry mouth, a factor leading to poor persistence. The β3-adrenoceptor agonist mirabegron is devoid of significant anticholinergic activity, while...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662398/

データ提供:米国国立医学図書館(NLM)

Overactive Bladder: A Search for Effective Treatments

In the vast desert of urology, researchers are constantly seeking new treatments to alleviate the discomfort of overactive bladder (OAB). This study explores the efficacy and persistence of mirabegron, a novel β3-adrenoceptor agonist, compared to antimuscarinics, the current mainstay of treatment for OAB. The authors investigate the use of mirabegron as a potential alternative to antimuscarinics, which are often plagued by anticholinergic side effects, leading to poor patient adherence. Their findings provide valuable insights into the potential of mirabegron as a new treatment option for OAB.

Mirabegron: A Promising Oasis in the Urological Desert

The study suggests that mirabegron, with its lack of significant anticholinergic activity, holds promise as a well-tolerated and effective treatment for OAB. The authors observed higher persistence and adherence rates with mirabegron compared to antimuscarinics, suggesting that mirabegron could potentially improve patient outcomes and satisfaction.

Navigating the Bladder Desert: Choosing the Right Treatment

The research emphasizes the importance of selecting the most appropriate treatment for OAB, balancing efficacy with tolerability. The study highlights the potential benefits of mirabegron as a new treatment option for patients seeking relief from OAB symptoms. Further research is needed to fully explore the long-term benefits and safety of mirabegron in treating OAB.

Dr. Camel's Conclusion

The desert of urology is filled with diverse landscapes and challenges, and OAB is no exception. This research offers a new oasis of hope with the advent of mirabegron, a novel treatment option that may offer improved tolerability and adherence compared to traditional antimuscarinics. By considering the unique needs of each patient, healthcare professionals can guide individuals toward a more comfortable and fulfilling journey through the bladder desert.

Date :
  1. Date Completed 2015-12-08
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

26644809

DOI: Digital Object Identifier

PMC4662398

Related Literature

SNS
PICO Info
in preparation
Languages

English

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