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The safety and efficacy of Avanafil, a new 2(nd) generation PDE5i: comprehensive review and meta-analysis.
Author: BurriAndrea, CoronaGiovanni, JanniniEmmanuele A, MaggiMario, RastrelliGiulia
Original Abstract of the Article :
INTRODUCTION: The discontinuation rate with phosphodiesterase type 5 inhibitors (PDE5i) remains very high. Recently, a new PDE5ì, avanafil, has become available worldwide. AREAS COVERED: All placebo-controlled randomized clinical trials (RCTs) on the effect of avanafil in patients with ED were revi...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元:
https://doi.org/10.1517/14740338.2016.1130126
データ提供:米国国立医学図書館(NLM)
Avanafil: A New Dawn in the Desert of Erectile Dysfunction
Erectile dysfunction (ED), a common condition that can significantly impact a man's quality of life, has long been a focus of medical research. Phosphodiesterase type 5 inhibitors (PDE5is), such as sildenafil and tadalafil, have become mainstay treatments for ED, but some men experience side effects or lack of efficacy with these medications. This study, my fellow researchers, examines the safety and efficacy of avanafil, a new generation PDE5i, offering a potential solution to address these challenges. The authors conducted a meta-analysis of clinical trials comparing avanafil to placebo, revealing its superior efficacy in achieving successful sexual intercourse. They also found that avanafil is well tolerated, with a lower incidence of side effects compared to first-generation PDE5is. These findings suggest that avanafil holds promise as a safe and effective treatment option for ED.
A New Oasis in the Desert of ED: Avanafil
This meta-analysis provides compelling evidence for the safety and efficacy of avanafil, a new generation PDE5i, highlighting its potential as a valuable treatment option for ED. The study's findings suggest that avanafil offers a viable alternative to existing treatments, addressing the limitations of first-generation PDE5is.
Navigating the Desert of Intimacy: Seeking Solutions for ED
The desert of intimacy can be a challenging and often uncomfortable place for men experiencing ED. As Dr. Camel, I’ve learned that navigating this terrain requires understanding and support. This research offers a glimmer of hope, providing a potential new solution to address this common and often sensitive condition.
Dr.Camel's Conclusion
This meta-analysis provides strong evidence for the efficacy and safety of avanafil, a new generation PDE5i, suggesting that it holds promise as a valuable treatment option for ED.
Date :
- Date Completed 2016-10-07
- Date Revised 2022-04-19
Further Info :
Related Literature
English
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