Intra-Articular Therapies in the Treatment of Hand Osteoarthritis: A Systematic Literature Review.

Author: KloppenburgMargreet, KroonFéline P B, RubioRoxana, SchoonesJan W

Paper Details 
Original Abstract of the Article :
BACKGROUND: Local treatments to alleviate symptoms in hand osteoarthritis (OA) are preferred, especially in elderly patients with comorbidities. Therefore, we have summarized the benefits and harms of intra-articular (IA) therapies. METHODS: We conducted a systematic literature review until May 201...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756050/

データ提供:米国国立医学図書館(NLM)

Intra-Articular Therapies for Hand Osteoarthritis: A Systematic Review

The desert of osteoarthritis research is vast and complex, with many different approaches to treating this debilitating condition. This systematic review focuses on the use of intra-articular (IA) therapies for hand osteoarthritis (OA), exploring the efficacy and safety of corticosteroids and hyaluronic acid (HA). The authors conduct a thorough analysis of 13 controlled trials, seeking answers to the question of whether these treatments offer relief from pain and improve functionality. Their findings suggest that while IA corticosteroids and HA may have a short-term safety profile, there is limited evidence to support their efficacy for CMC OA. The authors emphasize the need for further research to confirm the potential benefits of these treatments, particularly for IP OA.

Limited Evidence for the Efficacy of IA Therapies

This review suggests that the effectiveness of IA corticosteroids and HA for CMC OA may be limited, providing a cautionary note for clinicians and patients alike. While these treatments may be considered as a potential option, the lack of strong evidence calls for a more cautious approach, prioritizing other treatment modalities or further research. This research serves as a reminder that not all interventions are created equal, and a thorough evaluation of evidence is essential for making informed decisions.

The Importance of Evidence-Based Medicine

This review underscores the importance of evidence-based medicine in guiding clinical practice. Just as a camel relies on its instinct to navigate the desert, we must rely on scientific evidence to make informed decisions about patient care. This study highlights the need for high-quality research to provide clinicians with the information they need to offer their patients the best possible treatment options.

Dr.Camel's Conclusion

This research provides valuable insights into the effectiveness of IA therapies for hand OA, emphasizing the need for further research and a balanced approach to treatment. Just as the desert landscape is constantly changing, so too is our understanding of osteoarthritis. We must continue our journey of exploration, seeking new knowledge and evidence-based solutions to improve the lives of those affected by this debilitating condition.

Date :
  1. Date Completed 2016-10-06
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

26650235

DOI: Digital Object Identifier

PMC4756050

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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