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Is There Any Objective Improvement of Nocturia by Combination Treatment of Zolpidem and Alpha-Blocker Therapy for Unresponsive to Alpha-Blocker Monotherapy in Men with Lower Urinary Tract Symptoms?
Author: DooSeung Whan, KimJae Heon, SongYun Seob, YangWon Jae
Original Abstract of the Article :
OBJECTIVES: The aim of the present study was to determine whether administration of zolpidem, a nonbenzodiazepine sedative-hypnotic agent, at night would improve the nocturia unresponsive to alpha-blocker monotherapy in men with lower urinary tract symptoms (LUTS). METHODS: This was a prospective o...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/luts.12001
データ提供:米国国立医学図書館(NLM)
Zolpidem and Alpha-Blockers: A Potential Oasis for Nocturia
This study delves into the world of lower urinary tract symptoms (LUTS), a common condition that can affect quality of life. The authors investigated the effectiveness of combining zolpidem, a sleep aid, with alpha-blockers, a common treatment for LUTS, in managing nocturia, a condition characterized by frequent nighttime urination. It's like finding a new oasis in the desert of LUTS treatment options.
A Combined Approach to Managing Nocturia
The study found that combining zolpidem with alpha-blockers significantly reduced nocturia episodes in men who did not respond to alpha-blockers alone. The combination therapy led to improvements in sleep quality, overall urinary symptoms, and bladder function. The authors suggest that this combined approach may be a viable option for patients with persistent nocturia.
Improving Sleep and Bladder Control: Finding Balance in the Desert
This research highlights the potential benefits of combining zolpidem with alpha-blockers in managing nocturia. It suggests that this approach could lead to improved sleep quality and better bladder control. While further research is needed to confirm the long-term effects and optimal dosages, this finding offers hope for patients struggling with this common condition.
Dr. Camel's Conclusion
This research provides a glimmer of hope in the desert of LUTS treatment. The combination therapy explored in this study may offer a viable solution for patients who haven't found relief with alpha-blockers alone. Remember, just like finding a hidden oasis in the desert, finding the right treatment for LUTS can be a journey, but it's a journey worth taking.
Date :
- Date Completed 2015-12-17
- Date Revised 2015-12-15
Further Info :
Related Literature
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