Paper Details 
Original Abstract of the Article :
The Plasmodium falciparum telomerase reverse transcriptase (PfTERT) is a ribonucleoprotein that assists the maintenance of the telomeric ends of chromosomes by reverse transcription of its own RNA subunit. It represents an attractive therapeutic target for eradication of the plasmodial parasite at t...See full text at original site
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引用元:
https://doi.org/10.1089/adt.2015.29013.pmodrrr

データ提供:米国国立医学図書館(NLM)

Targeting Malaria at its Roots: Repurposing Nucleoside Analog Inhibitors

Malaria, a deadly parasitic disease, continues to plague many parts of the world. This study explores the potential of repurposing nucleoside analog inhibitors, a class of drugs currently used for other diseases, to target Plasmodium falciparum telomerase reverse transcriptase (PfTERT), a critical enzyme involved in the parasite's survival. The researchers used computational modeling to investigate the interactions of nucleoside analogs with PfTERT and identified several promising candidates for further investigation.

A New Weapon: Repurposing Drugs for Malaria Treatment

This study highlights the potential of repurposing existing drugs to combat malaria. It's like finding a hidden oasis in the desert of drug discovery, offering a new weapon in the fight against this devastating disease.

The Power of Repurposing: Unlocking New Treatments

This study exemplifies the potential of drug repurposing, a cost-effective and efficient approach to finding new treatments for diseases. By exploring the potential of existing drugs for new applications, we can accelerate the development of new therapies and make a real difference in the lives of patients.

Dr.Camel's Conclusion

This study is a ray of hope in the desert of malaria research. By repurposing existing drugs, we can potentially develop new and effective treatments for this devastating disease. It's a reminder that creativity and resourcefulness can lead to groundbreaking discoveries in the fight against disease.

Date :
  1. Date Completed 2016-09-26
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

26690766

DOI: Digital Object Identifier

10.1089/adt.2015.29013.pmodrrr

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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