Oral Cannabidiol does not Alter the Subjective, Reinforcing or Cardiovascular Effects of Smoked Cannabis.

Author: BabalonisShanna, BediGillinder, CooperZiva D, GrayKevin M, HaneyMargaret, LofwallMichelle R, MalcolmRobert J, McRae-ClarkAimee, NuzzoPaul A, SparenborgSteven, WalshSharon L

Paper Details 
Original Abstract of the Article :
Cannabidiol (CBD), a constituent of cannabis with few psychoactive effects, has been reported in some studies to attenuate certain aspects of Δ(9)-tetrahydrocannabinol (THC) intoxication. However, most studies have tested only one dose of CBD in combination with one dose of oral THC, making it diffi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908634/

データ提供:米国国立医学図書館(NLM)

CBD: Not a Cure-All for Cannabis Highs

Cannabidiol (CBD) has gained popularity for its potential therapeutic benefits. However, this study aimed to investigate whether CBD can actually reduce the psychoactive effects of THC, the main psychoactive compound in cannabis. The researchers conducted a randomized, double-blind study with multiple doses of CBD and smoked cannabis, measuring a range of effects, including subjective experiences, reinforcing properties, and cardiovascular responses. Their findings suggest that, contrary to some prior studies, CBD does not significantly alter the subjective, reinforcing, or cardiovascular effects of smoked cannabis. This study provides crucial evidence regarding the interaction between CBD and THC, offering valuable insights into the potential and limitations of CBD in managing cannabis intoxication.

CBD's Limited Impact on Cannabis Effects

The study suggests that CBD, while having other therapeutic applications, may not be effective in reducing the intoxicating effects of smoked cannabis. This finding challenges some previous assumptions about the interaction between CBD and THC, highlighting the need for further research to fully understand the complexities of their relationship.

The Importance of Careful Consideration in Cannabis Use

This study emphasizes the importance of careful consideration regarding cannabis use, particularly the potential effects of different cannabinoids, such as CBD and THC. Individuals should be aware that CBD may not mitigate the psychoactive effects of THC, and its use should be discussed with a healthcare professional.

Dr.Camel's Conclusion

Imagine a desert traveler seeking refuge from the intense heat of the sun. This study is like discovering that a certain type of desert plant, while having many beneficial properties, doesn't actually provide much shade. While CBD shows promise in other areas, this study suggests that it may not be a reliable way to mitigate the effects of THC. It's important to remember that even in the vast and often misunderstood world of cannabis, there's still much to discover about its complex effects.

Date :
  1. Date Completed 2018-01-15
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

26708108

DOI: Digital Object Identifier

PMC4908634

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.