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An indirect comparison and cost per responder analysis of adalimumab, methotrexate and apremilast in the treatment of methotrexate-naïve patients with psoriatic arthritis.

Author: BettsKeith A, FriedmanAlan, GanguliArijit, GriffithJenny, SignorovitchJames E, ZhouZheng-Yi

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study compares the response rates and incremental costs associated with different treatments for active psoriatic arthritis (PsA): methotrexate, apremilast, and biologics. The study aims to provide information for making informed treatment decisions based on effectiveness and cost.
Paper Details　
Original Abstract of the Article :
Apremilast was recently approved for the treatment of active psoriatic arthritis (PsA). However, no studies compare apremilast with methotrexate or biologic therapies, so its relative comparative efficacy remains unknown. This study compared the response rates and incremental costs per responder ass...See full text at original site
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引用元：
https://doi.org/10.1185/03007995.2016.1140026

データ提供：米国国立医学図書館（NLM）

Comparing Therapies for Psoriatic Arthritis: A Cost-Effective Approach

Navigating the complex world of psoriatic arthritis (PsA) treatment, much like navigating a vast desert, requires careful consideration of diverse therapeutic options. This study delves into the comparative efficacy and cost-effectiveness of three commonly used treatments for PsA: adalimumab, methotrexate, and apremilast.

A Cost-Effective Analysis of PsA Treatment

The study compared response rates and incremental costs per responder associated with each treatment option. This analysis, much like a skilled desert navigator assessing different routes, provides valuable insights for making informed decisions about treatment strategies. The study's findings can help clinicians and patients navigate the complex landscape of PsA treatment, finding the most effective and cost-effective path toward optimal outcomes.

Navigating the Desert of PsA Treatment

This study, like a caravan carefully navigating a challenging desert, emphasizes the importance of considering both efficacy and cost-effectiveness in PsA treatment. By providing a comparative analysis of different therapies, the study empowers clinicians and patients to make informed decisions that balance therapeutic benefits with financial considerations. This research, like a wellspring of knowledge in the desert of PsA management, offers valuable insights for improving the lives of those living with this chronic condition.

Dr.Camel's Conclusion

This study offers a valuable roadmap for navigating the complex world of psoriatic arthritis treatment, providing a cost-effective analysis of different therapies. By illuminating the cost per responder associated with each option, this research empowers clinicians and patients to make informed decisions that balance therapeutic benefits with financial considerations, much like a desert traveler choosing the most efficient route across the vast and challenging landscape.
Date :
  1. Date Completed 2016-12-13
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26743448

DOI: Digital Object Identifier

10.1185/03007995.2016.1140026

Related Literature

Article Analysis
・Effective treatment of psoriatic arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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