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Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement: a phase III, randomised, controlled trial (PALACE 3).
Author: AelionJacob, BirbaraCharles A, BirdPaul, BlancoFrancisco J, CrowleyJeffrey, EdwardsChristopher J, JaworskiJanusz, StevensRandall M, VesseyAdele, ZhanXiaojiang
Original Abstract of the Article :
OBJECTIVE: To evaluate apremilast treatment in patients with active psoriatic arthritis, including current skin involvement, despite prior therapy with conventional disease-modifying antirheumatic drugs and/or biologic agents. METHODS: Patients (N=505) were randomised (1:1:1) to placebo, apremilast...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893110/
データ提供:米国国立医学図書館(NLM)
Apremilast: A Oasis of Relief for Psoriatic Arthritis
Psoriatic arthritis, a chronic inflammatory disease, can feel like traversing a desert of pain and discomfort. This research explores a potential oasis of relief – apremilast, an oral phosphodiesterase 4 inhibitor. The researchers conducted a phase III, randomized controlled trial, like a scientific expedition, to assess the efficacy and safety of apremilast in patients with active psoriatic arthritis.
Apremilast: A Beacon of Hope for Psoriatic Arthritis
The research showed that apremilast can provide significant relief from psoriatic arthritis symptoms, like finding a hidden spring in the desert. The study, like a map of the desert, reveals that apremilast can improve both joint pain and skin lesions, leading to a better quality of life. It's like finding a cool breeze in the desert – a welcome respite from the heat of inflammation.
Managing Psoriatic Arthritis with Apremilast
This research provides hope for patients struggling with psoriatic arthritis, suggesting that apremilast can be a valuable tool in their journey to manage this complex disease. However, like any treatment, it's important to work closely with a healthcare professional to determine if apremilast is right for you and to monitor for any potential side effects.
Dr.Camel's Conclusion
Apremilast, like a well-placed oasis, can provide significant relief from psoriatic arthritis symptoms, offering a glimmer of hope for those navigating the challenges of this chronic disease.
Date :
- Date Completed 2017-05-23
- Date Revised 2022-04-09
Further Info :
Related Literature
English
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