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Two-year results of disease activity score (DAS)-remission-steered treatment strategies aiming at drug-free remission in early arthritis patients (the IMPROVED-study).

Author: AkdemirGülşah, AllaartCornelia F, BoerKirsten V C Wevers-de, Goekoop-RuitermanYvonne P, GrilletBernard A M, HeimansLotte, HuizingaTom W J, LardLeroy R, MolenaarEsmeralda T, PeetersAndreas J, Steup-BeekmanGerda M, de SonnavillePeter B J, van GroenendaelJohannes H L M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

After 2 years remission-steered treatment in early RA and UA patients, DAS-remission and DFR percentages were relatively low. Patients who achieved early remission more often achieved (drug-free) remission after 2 years than patients who needed additional treatment steps in the randomization arms, and more UA than RA patients achieved DFR.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Early suppression of disease activity in (rheumatoid) arthritis (RA) patients may result in drug-free remission and prevent damage. We assessed 2-year clinical and radiological outcomes of two disease activity score (DAS)-remission-steered treatment strategies in early arthritis patients...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721018/

データ提供：米国国立医学図書館（NLM）

Early Arthritis Treatment: A Camel's Journey Toward Drug-Free Remission

Early suppression of disease activity in arthritis is crucial for preventing joint damage and achieving long-term remission. This study investigates the effectiveness of two remission-steered treatment strategies in patients with early rheumatoid arthritis (RA) or undifferentiated arthritis (UA), aiming to achieve drug-free remission.

A Path to Remission: Achieving Drug-Free Relief

The study, spanning two years, found that while remission rates were relatively low overall, patients who achieved early remission were more likely to achieve drug-free remission compared to those requiring additional treatment steps. Furthermore, UA patients had a higher rate of drug-free remission compared to RA patients. These findings provide valuable insights into the potential of personalized treatment strategies, tailored to the specific needs of each patient, in achieving long-term remission.

Navigating the Arthritis Desert: A Camel's Guide to Treatment

The journey through arthritis can be as challenging as a camel's trek through a desert landscape. This study emphasizes the importance of early intervention and personalized treatment strategies, aiming to minimize the impact of this debilitating condition. By working closely with healthcare professionals, patients can navigate the complexities of arthritis, seeking the most effective treatment options to achieve long-term relief.

Dr. Camel's Conclusion

This study, much like a camel's journey through the desert, highlights the importance of persistence and adaptability in the treatment of early arthritis. While achieving drug-free remission is not always easy, this research provides valuable insights into effective strategies for managing disease activity and achieving long-term relief. By embracing personalized approaches and working closely with healthcare professionals, patients can navigate the challenging terrain of arthritis and find a path toward a better quality of life.
Date :
  1. Date Completed 2016-10-06
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

26794605

DOI: Digital Object Identifier

PMC4721018

Related Literature

Article Analysis
・Effective treatment of arthritis
SNS
PICO Info
in preparation
Languages

English

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