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Comparison of Famciclovir, Valaciclovir, and Brivudine Treatments in Adult Immunocompetent Patients With Herpes Zoster.

Author: CosansuNurcihan, ErdemMustafa Teoman, KaraRabia Oztas, SolakBerna, YaldizMahizer

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Brivudine, famciclovir, and valaciclovir are all effective in treating pain in acute herpes zoster (HZ). However, brivudine showed faster pain relief in severe cases, making it a potential first-choice treatment option.
Paper Details　
Original Abstract of the Article :
Herpes zoster (HZ) is a common disease characterized by the recurrence of varicella zoster, that stays dormant in sensory ganglia. The primary goal of this study was to compare efficiencies of famciclovir, valaciclovir, and brivudine in terms of pain relief in HZ patients. Records of patients who we...See full text at original site
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引用元：
https://doi.org/10.1097/MJT.0000000000000436

データ提供：米国国立医学図書館（NLM）

Comparing Famciclovir, Valaciclovir, and Brivudine for Herpes Zoster

Herpes zoster, commonly known as shingles, is a painful viral infection that can cause significant discomfort. This study compares the efficacy of three antiviral medications – famciclovir, valaciclovir, and brivudine – in treating herpes zoster in adult immunocompetent patients.

Brivudine: A Promising Treatment for Severe Cases

The study, based on retrospective analysis of patient records, found that all three medications were effective in treating herpes zoster pain. However, brivudine demonstrated a faster onset of pain relief in severe cases, with a significant reduction in pain intensity observed on day 3 compared to famciclovir and valaciclovir. It's like choosing the right tool for the job – each antiviral medication has its own strengths and weaknesses, and the best choice depends on the severity of the infection.

Considerations for Treatment

The study highlights the importance of individualized treatment decisions based on the severity of herpes zoster infection. While brivudine showed promise in severe cases, further research is needed to confirm its long-term efficacy and to assess its safety profile in comparison to other antiviral medications. It's a reminder that the journey to recovery from herpes zoster requires a careful assessment of individual needs and a strategic approach to treatment.

Dr.Camel's Conclusion

This retrospective analysis suggests that brivudine may be a valuable treatment option for patients with severe herpes zoster, offering faster pain relief compared to other antiviral medications. Further research is needed to confirm these findings and to determine the optimal use of each antiviral medication for specific patient populations. It's a reminder that the quest for effective treatment options for herpes zoster is an ongoing journey, with new insights and advancements emerging continuously.

Date :
  1. Date Completed 2019-03-19
  2. Date Revised 2019-03-19
Further Info :

Pubmed ID

26808358

DOI: Digital Object Identifier

10.1097/MJT.0000000000000436

SNS
PICO Info
in preparation
Languages

English

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